LINC00184

Summary

LINC00184 (long intergenic non-protein coding RNA 184, HGNC:37192) is a long non-coding RNA gene on chromosome 1q42.3.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:37192
Approved symbol	LINC00184
Name	long intergenic non-protein coding RNA 184
Location	1q42.3
Locus type	RNA, long non-coding
Status	Approved
Aliases	HANC, lnc-beta-Catm
Ensembl gene	ENSG00000224939
Ensembl biotype	lncRNA
Entrez	100302691
RNAcentral	URS000075D028 — lncRNA, 2281 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 2 — 2 lncRNA

ENST00000429269, ENST00000796406

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000429269 — 2 exons

Exon	Start	End
ENSE00001620425	234629311	234629747
ENSE00001771955	234632948	234634780

Expression profiles

Bgee: expression breadth ubiquitous, 203 present calls, max score 89.82.

FANTOM5 (CAGE): breadth tissue_specific, TPM avg 5.4128 / max 852.4153, expressed in 54 samples.

FANTOM5 promoters (9 alternative TSS)

Promoter ID	TPM avg	Samples expressed
9135	3.3481	43
9140	1.0431	39
9134	0.5188	33
9136	0.1977	32
9138	0.1342	36
9141	0.0572	30
9137	0.0529	29
9133	0.0351	16
9139	0.0256	16

Top tissues by expression

212 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
skeletal muscle tissue of rectus abdominis	UBERON:0004511	89.82	silver quality
vena cava	UBERON:0004087	89.63	gold quality
superficial temporal artery	UBERON:0001614	84.12	silver quality
sperm	CL:0000019	83.20	gold quality
epithelium of nasopharynx	UBERON:0001951	82.89	gold quality
cardia of stomach	UBERON:0001162	81.21	gold quality
caecum	UBERON:0001153	80.74	gold quality
pericardium	UBERON:0002407	80.10	gold quality
pharyngeal mucosa	UBERON:0000355	80.00	gold quality
body of tongue	UBERON:0011876	79.93	gold quality
tongue	UBERON:0001723	79.38	gold quality
lateral nuclear group of thalamus	UBERON:0002736	78.87	gold quality
ventral tegmental area	UBERON:0002691	78.71	gold quality
subthalamic nucleus	UBERON:0001906	78.67	gold quality
superior surface of tongue	UBERON:0007371	78.46	gold quality
gingival epithelium	UBERON:0001949	78.40	silver quality
trachea	UBERON:0003126	78.37	gold quality
cerebellar vermis	UBERON:0004720	78.33	gold quality
dorsal plus ventral thalamus	UBERON:0001897	78.29	gold quality
corpus callosum	UBERON:0002336	78.17	gold quality
inferior vagus X ganglion	UBERON:0005363	77.64	gold quality
saphenous vein	UBERON:0007318	77.49	gold quality
nipple	UBERON:0002030	77.31	gold quality
lateral globus pallidus	UBERON:0002476	77.29	gold quality
pylorus	UBERON:0001166	77.21	gold quality
pons	UBERON:0000988	77.08	gold quality
oocyte	CL:0000023	76.80	silver quality
dorsal root ganglion	UBERON:0000044	76.78	gold quality
mammary duct	UBERON:0001765	76.75	gold quality
superior vestibular nucleus	UBERON:0007227	76.41	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 0.

Experiment	Marker?	Max mean expression
E-ANND-3	no	2.28

Regulation

Is transcription factor: no

Literature-anchored findings (GeneRIF, showing 3)

• Long noncoding RNA LINC00184 facilitates the proliferation, metastasis, and adenine metabolism of cholangiocarcinoma via modulating hsa-miR-23b-3p/ANXA2 axis. (PMID:33913242)
• LINC00184 plays an oncogenic role in non-small cell lung cancer via regulation of the miR-524-5p/HMGB2 axis. (PMID:34651416)
• LncRNA LINC00184 promotes docetaxel resistance and immune escape via miR-105-5p/PD-L1 axis in prostate cancer. (PMID:34896914)

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.