LINC00200

Summary

LINC00200 (long intergenic non-protein coding RNA 200, HGNC:30974) is a long non-coding RNA gene on chromosome 10p15.3.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:30974
Approved symbol	LINC00200
Name	long intergenic non-protein coding RNA 200
Location	10p15.3
Locus type	RNA, long non-coding
Status	Approved
Aliases	FLJ40354
Ensembl gene	ENSG00000229205
Ensembl biotype	lncRNA
Entrez	399706
RNAcentral	URS00003472D5 — lncRNA, 2434 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 6 — 6 lncRNA

ENST00000425630, ENST00000583117, ENST00000647993, ENST00000652683, ENST00000655745, ENST00000666348

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000425630 — 3 exons

Exon	Start	End
ENSE00001615303	1160553	1160637
ENSE00001649006	1162547	1165112
ENSE00001762982	1159768	1159990

Expression profiles

Bgee: expression breadth ubiquitous, 121 present calls, max score 86.87.

FANTOM5 (CAGE): breadth tissue_specific, TPM avg 0.1140 / max 12.6616, expressed in 52 samples.

FANTOM5 promoters (1 alternative TSS)

Promoter ID	TPM avg	Samples expressed
103440	0.1140	52

Top tissues by expression

121 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
cortex of kidney	UBERON:0001225	86.87	gold quality
male germ line stem cell (sensu Vertebrata) in testis	CL:0000089 ∩ UBERON:0000473	85.06	gold quality
primordial germ cell in gonad	CL:0000670 ∩ UBERON:0000991	80.57	gold quality
sural nerve	UBERON:0015488	75.35	gold quality
hindlimb stylopod muscle	UBERON:0004252	64.68	gold quality
ventricular zone	UBERON:0003053	59.96	gold quality
testis	UBERON:0000473	58.92	gold quality
ganglionic eminence	UBERON:0004023	58.30	gold quality
corpus callosum	UBERON:0002336	58.27	gold quality
left testis	UBERON:0004533	57.92	gold quality
cortical plate	UBERON:0005343	57.79	silver quality
right testis	UBERON:0004534	56.48	gold quality
prefrontal cortex	UBERON:0000451	56.22	gold quality
adrenal tissue	UBERON:0018303	55.79	gold quality
substantia nigra	UBERON:0002038	55.68	gold quality
blood	UBERON:0000178	55.61	gold quality
C1 segment of cervical spinal cord	UBERON:0006469	54.80	gold quality
Ammon’s horn	UBERON:0001954	54.76	gold quality
amygdala	UBERON:0001876	54.43	gold quality
temporal lobe	UBERON:0001871	54.40	gold quality
frontal cortex	UBERON:0001870	53.72	gold quality
bone marrow	UBERON:0002371	53.57	silver quality
heart left ventricle	UBERON:0002084	53.04	gold quality
leukocyte	CL:0000738	52.90	silver quality
superior frontal gyrus	UBERON:0002661	52.85	gold quality
vermiform appendix	UBERON:0001154	52.72	gold quality
cerebral cortex	UBERON:0000956	52.54	gold quality
duodenum	UBERON:0002114	52.50	gold quality
lymph node	UBERON:0000029	52.41	gold quality
monocyte	CL:0000576	52.19	silver quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 0.

Experiment	Marker?	Max mean expression
E-ANND-3	no	1.46

Regulation

Is transcription factor: no

Literature-anchored findings (GeneRIF, showing 1)

• LINC00200 contributes to the chemoresistance to oxaliplatin of gastric cancer cells via regulating E2F1/RAD51 axis. (PMID:33822325)

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.