LINC00210

Summary

LINC00210 (long intergenic non-protein coding RNA 210, HGNC:37458) is a long non-coding RNA gene on chromosome 1q41.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:37458
Approved symbol	LINC00210
Name	long intergenic non-protein coding RNA 210
Location	1q41
Locus type	RNA, long non-coding
Status	Approved
Aliases	RP11-72L13.1
Ensembl gene	ENSG00000231814
Ensembl biotype	lncRNA
Entrez	100885798
RNAcentral	URS000075EB39 — lncRNA, 1604 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 2 — 2 lncRNA

ENST00000431637, ENST00000659987

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000431637 — 4 exons

Exon	Start	End
ENSE00001701981	217919584	217920804
ENSE00001779520	217918193	217918304
ENSE00001788458	217892900	217892926
ENSE00001805614	217911758	217911981

Expression profiles

Bgee: expression breadth broad, 33 present calls, max score 88.85.

Top tissues by expression

33 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
male germ line stem cell (sensu Vertebrata) in testis	CL:0000089 ∩ UBERON:0000473	88.85	gold quality
cortical plate	UBERON:0005343	62.97	gold quality
monocyte	CL:0000576	58.32	gold quality
ganglionic eminence	UBERON:0004023	55.93	silver quality
kidney	UBERON:0002113	55.25	gold quality
heart	UBERON:0000948	54.93	gold quality
endometrium	UBERON:0001295	51.40	silver quality
heart left ventricle	UBERON:0002084	50.14	gold quality
frontal cortex	UBERON:0001870	49.97	gold quality
blood	UBERON:0000178	49.03	silver quality
lymph node	UBERON:0000029	47.52	silver quality
prefrontal cortex	UBERON:0000451	47.41	silver quality
gastrocnemius	UBERON:0001388	46.61	gold quality
tibial artery	UBERON:0007610	45.90	silver quality
olfactory segment of nasal mucosa	UBERON:0005386	45.13	silver quality
islet of Langerhans	UBERON:0000006	44.67	silver quality
dorsolateral prefrontal cortex	UBERON:0009834	44.67	silver quality
brain	UBERON:0000955	42.30	silver quality
vagina	UBERON:0000996	41.98	gold quality
lower esophagus muscularis layer	UBERON:0035833	41.89	gold quality
Ammon’s horn	UBERON:0001954	39.86	silver quality
substantia nigra	UBERON:0002038	38.87	silver quality
upper lobe of left lung	UBERON:0008952	38.19	silver quality
left lobe of thyroid gland	UBERON:0001120	38.04	silver quality
fallopian tube	UBERON:0003889	37.97	silver quality
anterior cingulate cortex	UBERON:0009835	37.45	silver quality
skin of abdomen	UBERON:0001416	37.05	silver quality
tibial nerve	UBERON:0001323	35.80	silver quality
esophagogastric junction muscularis propria	UBERON:0035841	35.54	silver quality
prostate gland	UBERON:0002367	35.47	silver quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 0.

Experiment	Marker?	Max mean expression
E-ANND-3	no	1.63

Regulation

Is transcription factor: no

Literature-anchored findings (GeneRIF, showing 3)

• Through inhibiting miR-328-5p activity, LINC00210 promoted NOTCH3 expression in nasopharyngeal carcinoma (NPC), leading to activation of NOTCH3 signaling pathway. In conclusion, our study indicates LINC00210 promotes NPC progression through modulating proliferation and invasion. (PMID:30341249)
• LncRNA LINC00210 regulated radiosensitivity of osteosarcoma cells via miR-342-3p/GFRA1 axis. (PMID:32841458)
• Long noncoding RNA Linc00210 promotes non-small cell lung cancer progression via sponging miR-16-5p/PTK2 axis. (PMID:33015786)

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.