LINC00216

Summary

LINC00216 (long intergenic non-protein coding RNA 216, HGNC:20191) is a long non-coding RNA gene on chromosome 14q23.1.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:20191
Approved symbol	LINC00216
Name	long intergenic non-protein coding RNA 216
Location	14q23.1
Locus type	RNA, long non-coding
Status	Approved
Aliases	PRO1617
Ensembl gene	ENSG00000279636
Ensembl biotype	lncRNA
Entrez	55451
RNAcentral	URS0000BC4552 — lncRNA, 1134 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 2 — 2 lncRNA

ENST00000623548, ENST00000627309

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000623548 — 1 exons

Exon	Start	End
ENSE00003755389	58288033	58289158

Expression profiles

Bgee: expression breadth ubiquitous, 169 present calls, max score 83.20.

Top tissues by expression

285 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
sural nerve	UBERON:0015488	83.20	gold quality
colonic epithelium	UBERON:0000397	80.13	gold quality
male germ line stem cell (sensu Vertebrata) in testis	CL:0000089 ∩ UBERON:0000473	79.61	gold quality
adrenal tissue	UBERON:0018303	77.22	gold quality
calcaneal tendon	UBERON:0003701	75.46	gold quality
tendon	UBERON:0000043	72.19	gold quality
tendon of biceps brachii	UBERON:0008188	70.32	silver quality
bone marrow cell	CL:0002092	68.93	gold quality
cortical plate	UBERON:0005343	68.68	gold quality
medial globus pallidus	UBERON:0002477	66.13	gold quality
monocyte	CL:0000576	65.81	gold quality
mononuclear cell	CL:0000842	65.66	gold quality
tibialis anterior	UBERON:0001385	65.19	silver quality
ganglionic eminence	UBERON:0004023	64.38	gold quality
corpus callosum	UBERON:0002336	63.81	gold quality
primordial germ cell in gonad	CL:0000670 ∩ UBERON:0000991	62.99	gold quality
stromal cell of endometrium	CL:0002255	61.92	gold quality
ventricular zone	UBERON:0003053	61.61	gold quality
lower esophagus mucosa	UBERON:0035834	60.99	gold quality
tonsil	UBERON:0002372	60.78	gold quality
globus pallidus	UBERON:0001875	60.69	silver quality
left ovary	UBERON:0002119	58.05	gold quality
pancreatic ductal cell	CL:0002079	57.83	silver quality
adenohypophysis	UBERON:0002196	57.82	gold quality
body of uterus	UBERON:0009853	57.01	gold quality
right lobe of thyroid gland	UBERON:0001119	56.89	gold quality
endocervix	UBERON:0000458	56.87	gold quality
right lobe of liver	UBERON:0001114	56.60	gold quality
pituitary gland	UBERON:0000007	56.55	gold quality
right ovary	UBERON:0002118	56.45	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 0.

Experiment	Marker?	Max mean expression
E-ANND-3	no	1.47

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.