LINC00226

Summary

LINC00226 (long intergenic non-protein coding RNA 226, HGNC:20168) is a long non-coding RNA gene on chromosome 14q32.33.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:20168
Approved symbol	LINC00226
Name	long intergenic non-protein coding RNA 226
Location	14q32.33
Locus type	RNA, long non-coding
Status	Approved
Ensembl gene	ENSG00000276210
Ensembl biotype	lncRNA
Entrez	338004
RNAcentral	URS000075D64F — lncRNA, 596 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 2 — 2 lncRNA

ENST00000611530, ENST00000618204

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000611530 — 2 exons

Exon	Start	End
ENSE00003724949	106288044	106288372
ENSE00003725987	106287720	106287962

Expression profiles

Bgee: expression breadth broad, 49 present calls, max score 93.09.

FANTOM5 (CAGE): breadth tissue_specific, TPM avg 0.0378 / max 44.2063, expressed in 3 samples.

FANTOM5 promoters (2 alternative TSS)

Promoter ID	TPM avg	Samples expressed
141992	0.0244	3
141991	0.0134	3

Top tissues by expression

179 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
sperm	CL:0000019	93.09	gold quality
male germ line stem cell (sensu Vertebrata) in testis	CL:0000089 ∩ UBERON:0000473	91.21	gold quality
left testis	UBERON:0004533	86.64	gold quality
right testis	UBERON:0004534	85.86	gold quality
testis	UBERON:0000473	84.48	gold quality
primordial germ cell in gonad	CL:0000670 ∩ UBERON:0000991	75.15	gold quality
adult organism	UBERON:0007023	66.28	gold quality
left ventricle myocardium	UBERON:0006566	65.55	gold quality
cardiac muscle of right atrium	UBERON:0003379	64.98	gold quality
myocardium	UBERON:0002349	55.99	gold quality
islet of Langerhans	UBERON:0000006	54.79	gold quality
monocyte	CL:0000576	53.96	gold quality
kidney epithelium	UBERON:0004819	53.93	gold quality
epithelial cell of pancreas	CL:0000083	53.61	gold quality
upper arm skin	UBERON:0004263	53.52	gold quality
buccal mucosa cell	CL:0002336	53.44	gold quality
pancreatic ductal cell	CL:0002079	51.44	silver quality
upper lobe of lung	UBERON:0008948	50.98	silver quality
lower lobe of lung	UBERON:0008949	50.79	silver quality
tibial nerve	UBERON:0001323	50.68	gold quality
vermiform appendix	UBERON:0001154	50.52	gold quality
muscle of leg	UBERON:0001383	48.70	gold quality
gastrocnemius	UBERON:0001388	48.15	gold quality
prefrontal cortex	UBERON:0000451	47.99	gold quality
tibialis anterior	UBERON:0001385	47.95	silver quality
deltoid	UBERON:0001476	47.93	gold quality
ileal mucosa	UBERON:0000331	47.44	silver quality
body of uterus	UBERON:0009853	47.33	gold quality
nasal cavity epithelium	UBERON:0005384	47.03	gold quality
anatomical system	UBERON:0000467	46.63	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 0.

Experiment	Marker?	Max mean expression
E-ANND-3	no	0.00

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.