LINC00243

Summary

LINC00243 (long intergenic non-protein coding RNA 243, HGNC:30956) is a long non-coding RNA gene on chromosome 6p21.33.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:30956
Approved symbol	LINC00243
Name	long intergenic non-protein coding RNA 243
Location	6p21.33
Locus type	RNA, long non-coding
Status	Approved
Aliases	bQB230F21.2, FLJ40693, bQB10J12.2
Ensembl gene	ENSG00000214894
Ensembl biotype	lncRNA
Entrez	401247
RNAcentral	URS00007C13E2 — lncRNA, 2052 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 16 — 16 lncRNA

ENST00000399196, ENST00000419357, ENST00000719489, ENST00000719490, ENST00000719491, ENST00000719492, ENST00000719493, ENST00000719494, ENST00000719495, ENST00000719496, ENST00000719497, ENST00000719498, ENST00000719499, ENST00000719500, ENST00000719501, ENST00000719502

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000399196 — 2 exons

Exon	Start	End
ENSE00001792970	30812866	30814772
ENSE00004037271	30830515	30830659

Expression profiles

Bgee: expression breadth ubiquitous, 121 present calls, max score 80.94.

FANTOM5 (CAGE): breadth tissue_specific, TPM avg 0.6615 / max 47.2715, expressed in 110 samples.

FANTOM5 promoters (3 alternative TSS)

Promoter ID	TPM avg	Samples expressed
72613	0.6101	106
72614	0.0430	28
72615	0.0085	3

Top tissues by expression

121 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
primordial germ cell in gonad	CL:0000670 ∩ UBERON:0000991	80.94	gold quality
sural nerve	UBERON:0015488	78.12	silver quality
granulocyte	CL:0000094	76.38	gold quality
blood	UBERON:0000178	76.04	gold quality
lymph node	UBERON:0000029	75.81	gold quality
male germ line stem cell (sensu Vertebrata) in testis	CL:0000089 ∩ UBERON:0000473	75.10	silver quality
vermiform appendix	UBERON:0001154	73.57	gold quality
skeletal muscle tissue	UBERON:0001134	69.71	gold quality
tonsil	UBERON:0002372	69.18	gold quality
leukocyte	CL:0000738	68.25	gold quality
monocyte	CL:0000576	67.06	gold quality
bone marrow cell	CL:0002092	66.61	silver quality
spleen	UBERON:0002106	65.76	gold quality
colonic epithelium	UBERON:0000397	64.36	silver quality
bone marrow	UBERON:0002371	60.99	gold quality
mucosa of transverse colon	UBERON:0004991	60.71	gold quality
smooth muscle tissue	UBERON:0001135	59.99	gold quality
small intestine Peyer’s patch	UBERON:0003454	59.75	gold quality
placenta	UBERON:0001987	59.27	gold quality
small intestine	UBERON:0002108	59.07	gold quality
liver	UBERON:0002107	58.70	gold quality
urinary bladder	UBERON:0001255	58.27	gold quality
right lobe of liver	UBERON:0001114	57.69	gold quality
ganglionic eminence	UBERON:0004023	57.69	silver quality
corpus callosum	UBERON:0002336	57.52	gold quality
gall bladder	UBERON:0002110	57.06	gold quality
ectocervix	UBERON:0012249	55.77	gold quality
islet of Langerhans	UBERON:0000006	55.12	gold quality
endometrium	UBERON:0001295	54.63	gold quality
olfactory segment of nasal mucosa	UBERON:0005386	54.52	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 0.

Experiment	Marker?	Max mean expression
E-ANND-3	no	1.00

Regulation

Is transcription factor: no

Literature-anchored findings (GeneRIF, showing 1)

• LINC00243 modulated expression of endogenous miR-507-targeted PDK4. LINC00243 promotes proliferation and glycolysis in NSCLC cells by positively regulating PDK4 through sponging miR-507. (PMID:31595421)

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.