LINC00251

Summary

LINC00251 (long intergenic non-protein coding RNA 251, HGNC:31950) is a long non-coding RNA gene on chromosome 8q13.1.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:31950
Approved symbol	LINC00251
Name	long intergenic non-protein coding RNA 251
Location	8q13.1
Locus type	RNA, long non-coding
Status	Approved
Ensembl gene	ENSG00000280725
Ensembl biotype	lncRNA
Entrez	552859
RNAcentral	URS000075C711 — lncRNA, 1058 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 4 — 4 lncRNA

ENST00000627569, ENST00000650029, ENST00000818470, ENST00000818471

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000627569 — 4 exons

Exon	Start	End
ENSE00003764996	65172334	65172512
ENSE00003767232	65161145	65161769
ENSE00003769155	65180198	65180341
ENSE00003769609	65175673	65175779

Expression profiles

Bgee: expression breadth broad, 35 present calls, max score 91.41.

Top tissues by expression

35 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
male germ line stem cell (sensu Vertebrata) in testis	CL:0000089 ∩ UBERON:0000473	91.41	gold quality
thoracic mammary gland	UBERON:0005200	61.34	gold quality
left testis	UBERON:0004533	60.66	gold quality
testis	UBERON:0000473	60.30	gold quality
hindlimb stylopod muscle	UBERON:0004252	58.21	silver quality
right testis	UBERON:0004534	57.68	gold quality
blood	UBERON:0000178	53.07	silver quality
liver	UBERON:0002107	52.15	silver quality
prefrontal cortex	UBERON:0000451	52.12	gold quality
fundus of stomach	UBERON:0001160	51.81	gold quality
superior frontal gyrus	UBERON:0002661	50.96	gold quality
multicellular organism	UBERON:0000468	50.27	gold quality
gastrocnemius	UBERON:0001388	49.90	gold quality
skin of leg	UBERON:0001511	48.22	gold quality
Brodmann (1909) area 9	UBERON:0013540	47.57	gold quality
frontal cortex	UBERON:0001870	46.80	gold quality
dorsolateral prefrontal cortex	UBERON:0009834	46.04	gold quality
stomach	UBERON:0000945	44.44	gold quality
adipose tissue	UBERON:0001013	44.24	gold quality
subcutaneous adipose tissue	UBERON:0002190	43.78	gold quality
body of stomach	UBERON:0001161	43.53	gold quality
hypothalamus	UBERON:0001898	43.37	silver quality
amygdala	UBERON:0001876	42.75	gold quality
brain	UBERON:0000955	42.12	gold quality
substantia nigra	UBERON:0002038	41.60	gold quality
putamen	UBERON:0001874	41.54	silver quality
Ammon’s horn	UBERON:0001954	41.38	silver quality
C1 segment of cervical spinal cord	UBERON:0006469	40.49	silver quality
prostate gland	UBERON:0002367	39.62	gold quality
tibial artery	UBERON:0007610	39.50	silver quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 1.

Experiment	Marker?	Max mean expression
E-ANND-3	yes	2.78

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.