LINC00254

Summary

LINC00254 (long intergenic non-protein coding RNA 254, HGNC:14160) is a long non-coding RNA gene on chromosome 16p13.3.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:14160
Approved symbol	LINC00254
Name	long intergenic non-protein coding RNA 254
Location	16p13.3
Locus type	RNA, long non-coding
Status	Approved
Ensembl gene	ENSG00000281219
Ensembl biotype	lncRNA
Entrez	64735
RNAcentral	URS000075D281 — lncRNA, 672 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 2 — 2 lncRNA

ENST00000563416, ENST00000633813

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000563416 — 3 exons

Exon	Start	End
ENSE00002606411	1884097	1884231
ENSE00002613814	1878285	1878710
ENSE00003771138	1883196	1883296

Expression profiles

Bgee: expression breadth broad, 47 present calls, max score 84.74.

Top tissues by expression

47 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
male germ line stem cell (sensu Vertebrata) in testis	CL:0000089 ∩ UBERON:0000473	84.74	gold quality
left testis	UBERON:0004533	65.23	gold quality
right testis	UBERON:0004534	65.01	gold quality
testis	UBERON:0000473	64.80	gold quality
blood	UBERON:0000178	55.18	gold quality
multicellular organism	UBERON:0000468	53.50	gold quality
monocyte	CL:0000576	53.33	silver quality
right lobe of liver	UBERON:0001114	49.71	gold quality
vagina	UBERON:0000996	48.86	gold quality
gastrocnemius	UBERON:0001388	48.52	gold quality
tibial nerve	UBERON:0001323	47.90	gold quality
left lobe of thyroid gland	UBERON:0001120	47.03	gold quality
tibial artery	UBERON:0007610	45.45	gold quality
body of pancreas	UBERON:0001150	45.15	silver quality
ascending aorta	UBERON:0001496	45.05	gold quality
esophagus	UBERON:0001043	44.78	gold quality
right ovary	UBERON:0002118	43.83	gold quality
Ammon’s horn	UBERON:0001954	43.70	silver quality
skin of leg	UBERON:0001511	43.66	gold quality
zone of skin	UBERON:0000014	43.63	gold quality
left coronary artery	UBERON:0001626	43.44	gold quality
esophagus mucosa	UBERON:0002469	43.12	gold quality
left adrenal gland	UBERON:0001234	42.95	silver quality
C1 segment of cervical spinal cord	UBERON:0006469	42.83	gold quality
esophagogastric junction muscularis propria	UBERON:0035841	42.74	silver quality
skin of abdomen	UBERON:0001416	42.68	gold quality
transverse colon	UBERON:0001157	41.68	silver quality
Brodmann (1909) area 9	UBERON:0013540	41.60	silver quality
upper lobe of left lung	UBERON:0008952	41.52	silver quality
subcutaneous adipose tissue	UBERON:0002190	40.79	silver quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 0.

Experiment	Marker?	Max mean expression
E-ANND-3	no	0.08

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.