LINC00276

Summary

LINC00276 (long intergenic non-protein coding RNA 276, HGNC:38663) is a long non-coding RNA gene on chromosome 2p24.3.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:38663
Approved symbol	LINC00276
Name	long intergenic non-protein coding RNA 276
Location	2p24.3
Locus type	RNA, long non-coding
Status	Approved
Ensembl gene	ENSG00000230448
Ensembl biotype	lncRNA
Entrez	100499171
RNAcentral	URS00007E3364 — lncRNA, 3518 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 4 — 4 lncRNA

ENST00000417751, ENST00000418420, ENST00000720689, ENST00000747982

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000417751 — 5 exons

Exon	Start	End
ENSE00001625128	14400843	14400963
ENSE00001630215	13739187	13739284
ENSE00001661477	14316969	14317103
ENSE00001774166	13710531	13710721
ENSE00001788959	13841564	13841614

Expression profiles

Bgee: expression breadth ubiquitous, 107 present calls, max score 78.19.

FANTOM5 (CAGE): breadth tissue_specific, TPM avg 0.0245 / max 23.8559, expressed in 7 samples.

FANTOM5 promoters (2 alternative TSS)

Promoter ID	TPM avg	Samples expressed
26946	0.0175	6
26947	0.0070	3

Top tissues by expression

205 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
buccal mucosa cell	CL:0002336	78.19	silver quality
primordial germ cell in gonad	CL:0000670 ∩ UBERON:0000991	75.32	gold quality
male germ line stem cell (sensu Vertebrata) in testis	CL:0000089 ∩ UBERON:0000473	74.35	gold quality
pigmented layer of retina	UBERON:0001782	70.07	gold quality
hindlimb stylopod muscle	UBERON:0004252	67.85	gold quality
sural nerve	UBERON:0015488	63.38	gold quality
ganglionic eminence	UBERON:0004023	62.63	gold quality
right lobe of thyroid gland	UBERON:0001119	57.31	gold quality
olfactory segment of nasal mucosa	UBERON:0005386	56.40	gold quality
monocyte	CL:0000576	55.20	gold quality
left lobe of thyroid gland	UBERON:0001120	54.76	gold quality
thyroid gland	UBERON:0002046	54.63	gold quality
adrenal tissue	UBERON:0018303	54.12	gold quality
islet of Langerhans	UBERON:0000006	52.31	gold quality
lower lobe of lung	UBERON:0008949	51.95	silver quality
corpus callosum	UBERON:0002336	51.46	gold quality
calcaneal tendon	UBERON:0003701	50.51	silver quality
right lobe of liver	UBERON:0001114	48.86	silver quality
prefrontal cortex	UBERON:0000451	48.80	gold quality
gastrocnemius	UBERON:0001388	48.51	silver quality
substantia nigra pars reticulata	UBERON:0001966	47.52	gold quality
pancreas	UBERON:0001264	46.85	gold quality
descending thoracic aorta	UBERON:0002345	46.55	gold quality
ectocervix	UBERON:0012249	46.35	gold quality
ovary	UBERON:0000992	46.11	silver quality
left adrenal gland cortex	UBERON:0035825	45.87	gold quality
right ovary	UBERON:0002118	45.83	gold quality
tendon	UBERON:0000043	45.53	silver quality
upper lobe of lung	UBERON:0008948	45.06	silver quality
body of pancreas	UBERON:0001150	44.96	silver quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 1.

Experiment	Marker?	Max mean expression
E-ANND-3	no	0.00

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.