LINC00280

Summary

LINC00280 (long intergenic non-protein coding RNA 280, HGNC:38803) is a long non-coding RNA gene on chromosome Yp11.2.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:38803
Approved symbol	LINC00280
Name	long intergenic non-protein coding RNA 280
Location	Yp11.2
Locus type	RNA, long non-coding
Status	Approved
Ensembl gene	ENSG00000229643
Ensembl biotype	lncRNA
Entrez	100873964
RNAcentral	URS00003A022F — lncRNA, 448 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 2 — 2 lncRNA

ENST00000439525, ENST00000652050

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000439525 — 3 exons

Exon	Start	End
ENSE00001660336	6358684	6358826
ENSE00001671403	6361328	6361413
ENSE00001785311	6357219	6357437

Expression profiles

Bgee: expression breadth broad, 53 present calls, max score 82.72.

Top tissues by expression

53 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
male germ line stem cell (sensu Vertebrata) in testis	CL:0000089 ∩ UBERON:0000473	82.72	gold quality
ganglionic eminence	UBERON:0004023	57.01	silver quality
saliva-secreting gland	UBERON:0001044	53.01	gold quality
minor salivary gland	UBERON:0001830	52.90	gold quality
heart left ventricle	UBERON:0002084	52.11	gold quality
gastrocnemius	UBERON:0001388	51.29	gold quality
blood	UBERON:0000178	50.51	gold quality
fundus of stomach	UBERON:0001160	48.86	gold quality
muscle layer of sigmoid colon	UBERON:0035805	48.33	gold quality
liver	UBERON:0002107	47.97	silver quality
prefrontal cortex	UBERON:0000451	47.81	gold quality
tibial artery	UBERON:0007610	47.16	gold quality
cerebellar hemisphere	UBERON:0002245	47.09	silver quality
right atrium auricular region	UBERON:0006631	45.40	gold quality
subcutaneous adipose tissue	UBERON:0002190	45.07	gold quality
putamen	UBERON:0001874	44.88	gold quality
small intestine	UBERON:0002108	44.33	gold quality
transverse colon	UBERON:0001157	44.08	gold quality
body of stomach	UBERON:0001161	43.79	silver quality
omental fat pad	UBERON:0010414	43.70	gold quality
ascending aorta	UBERON:0001496	43.63	gold quality
esophagogastric junction muscularis propria	UBERON:0035841	43.29	silver quality
frontal cortex	UBERON:0001870	43.22	gold quality
right lung	UBERON:0002167	43.06	gold quality
lower esophagus	UBERON:0013473	43.06	silver quality
lower esophagus muscularis layer	UBERON:0035833	43.04	silver quality
Brodmann (1909) area 9	UBERON:0013540	42.78	silver quality
superior frontal gyrus	UBERON:0002661	42.63	silver quality
small intestine Peyer’s patch	UBERON:0003454	42.45	gold quality
dorsolateral prefrontal cortex	UBERON:0009834	42.41	silver quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 0.

Experiment	Marker?	Max mean expression
E-ANND-3	no	0.00

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.