LINC00290
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Summary
LINC00290 (long intergenic non-protein coding RNA 290, HGNC:38515) is a long non-coding RNA gene on chromosome 4q34.3.
At a glance
- Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).
Identifiers
Gene identifiers
| Field | Value |
|---|---|
| HGNC ID | HGNC:38515 |
| Approved symbol | LINC00290 |
| Name | long intergenic non-protein coding RNA 290 |
| Location | 4q34.3 |
| Locus type | RNA, long non-coding |
| Status | Approved |
| Ensembl gene | ENSG00000248197 |
| Ensembl biotype | lncRNA |
| Entrez | 728081 |
| RNAcentral | URS000075A4B6 — lncRNA, 600 nt, 1 organism(s) |
Gene structure
Transcript identifiers
Ensembl transcripts: 14 — 14 lncRNA
ENST00000512487, ENST00000778348, ENST00000778349, ENST00000778350, ENST00000778351, ENST00000778352, ENST00000778353, ENST00000778354, ENST00000778355, ENST00000778356, ENST00000778357, ENST00000778358, ENST00000778359, ENST00000778360
RefSeq mRNA: 0 — MANE Select: None
Canonical transcript exons
ENST00000512487 — 3 exons
| Exon | Start | End |
|---|---|---|
| ENSE00002045839 | 181155613 | 181155739 |
| ENSE00004147715 | 181159076 | 181159473 |
| ENSE00004147724 | 181064024 | 181064480 |
Expression profiles
Bgee: expression breadth broad, 66 present calls, max score 73.01.
Top tissues by expression
176 total, by Bgee expression score (0-100, higher = more expressed):
| Tissue | Anatomy ID | Expression score | Quality |
|---|---|---|---|
| adrenal tissue | UBERON:0018303 | 73.01 | gold quality |
| caudate nucleus | UBERON:0001873 | 66.33 | gold quality |
| nucleus accumbens | UBERON:0001882 | 66.17 | gold quality |
| putamen | UBERON:0001874 | 65.71 | gold quality |
| cortical plate | UBERON:0005343 | 64.76 | gold quality |
| buccal mucosa cell | CL:0002336 | 61.62 | gold quality |
| prefrontal cortex | UBERON:0000451 | 59.95 | gold quality |
| anterior cingulate cortex | UBERON:0009835 | 58.14 | gold quality |
| amygdala | UBERON:0001876 | 57.91 | gold quality |
| hypothalamus | UBERON:0001898 | 56.80 | gold quality |
| Brodmann (1909) area 9 | UBERON:0013540 | 56.70 | gold quality |
| forebrain | UBERON:0001890 | 55.79 | gold quality |
| islet of Langerhans | UBERON:0000006 | 55.37 | gold quality |
| primordial germ cell in gonad | CL:0000670 ∩ UBERON:0000991 | 55.19 | gold quality |
| brain | UBERON:0000955 | 54.73 | gold quality |
| neocortex | UBERON:0001950 | 53.77 | gold quality |
| dorsolateral prefrontal cortex | UBERON:0009834 | 53.74 | gold quality |
| lower lobe of lung | UBERON:0008949 | 53.71 | silver quality |
| upper lobe of lung | UBERON:0008948 | 53.53 | silver quality |
| Ammon’s horn | UBERON:0001954 | 53.24 | gold quality |
| frontal cortex | UBERON:0001870 | 53.01 | gold quality |
| cerebral cortex | UBERON:0000956 | 52.67 | gold quality |
| right frontal lobe | UBERON:0002810 | 52.36 | gold quality |
| temporal lobe | UBERON:0001871 | 52.24 | gold quality |
| pancreas | UBERON:0001264 | 51.06 | gold quality |
| substantia nigra | UBERON:0002038 | 49.47 | gold quality |
| adrenal gland | UBERON:0002369 | 49.31 | gold quality |
| tendon of biceps brachii | UBERON:0008188 | 48.92 | gold quality |
| monocyte | CL:0000576 | 48.90 | silver quality |
| muscle of leg | UBERON:0001383 | 48.36 | gold quality |
Single-cell (SCXA)
Detected in 1 experiment(s), a significant marker in 0.
| Experiment | Marker? | Max mean expression |
|---|---|---|
| E-ANND-3 | no | 1.97 |
Regulation
Is transcription factor: no
Cross-species orthologs
0 orthologs
Protein
Non-coding RNA — no protein product; not a drug target.
Function
No curated pathway, Gene-Ontology, or interaction data.
Disease & clinical
No curated disease, variant, or cancer-driver associations.
Drugs & pharmacology
No drug or pharmacology data — not an established drug target.
Related Atlas pages
- Disease cohort memberships (association, not causation — diseases whose associated-gene cohort lists this gene; a subset are also under Associated diseases): cerebral amyloid angiopathy, human papilloma virus infection, small cell lung carcinoma