LINC00293

Summary

LINC00293 (long intergenic non-protein coding RNA 293, HGNC:39078) is a long non-coding RNA gene on chromosome 8q11.1.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:39078
Approved symbol	LINC00293
Name	long intergenic non-protein coding RNA 293
Location	8q11.1
Locus type	RNA, long non-coding
Status	Approved
Aliases	BEYLA
Ensembl gene	ENSG00000253314
Ensembl biotype	lncRNA
OMIM	609543
Entrez	497634
RNAcentral	URS000075BED8 — lncRNA, 2149 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 130 — 130 lncRNA

ENST00000518278, ENST00000518962, ENST00000519008, ENST00000521715, ENST00000652776, ENST00000652884, ENST00000653009, ENST00000653031, ENST00000653191, ENST00000653268, ENST00000653350, ENST00000653482, ENST00000653792, ENST00000653831, ENST00000653880, ENST00000654114, ENST00000654290, ENST00000654720, ENST00000654740, ENST00000654833, ENST00000654936, ENST00000655128, ENST00000655178, ENST00000655218, ENST00000655527, ENST00000655669, ENST00000655710, ENST00000656186, ENST00000656283, ENST00000656305, ENST00000656438, ENST00000656924, ENST00000657020, ENST00000657159, ENST00000657336, ENST00000657416, ENST00000657437, ENST00000657592, ENST00000657676, ENST00000657890, ENST00000658134, ENST00000658145, ENST00000658235, ENST00000658631, ENST00000658758, ENST00000658839, ENST00000658902, ENST00000659003, ENST00000659041, ENST00000659384, ENST00000659403, ENST00000659425, ENST00000659649, ENST00000660162, ENST00000660234, ENST00000660279, ENST00000660440, ENST00000660686, ENST00000660735, ENST00000660984, ENST00000661199, ENST00000661270, ENST00000661276, ENST00000661462, ENST00000661775, ENST00000661796, ENST00000661882, ENST00000661934, ENST00000662003, ENST00000662050, ENST00000662135, ENST00000662230, ENST00000662711, ENST00000662731, ENST00000663175, ENST00000663295, ENST00000663826, ENST00000663886, ENST00000664124, ENST00000664450, ENST00000664596, ENST00000664619, ENST00000664843, ENST00000664867, ENST00000664932, ENST00000664955, ENST00000665258, ENST00000665463, ENST00000665520, ENST00000665900, ENST00000665915, ENST00000666036, ENST00000666038, ENST00000666069, ENST00000666272, ENST00000666516, ENST00000666661, ENST00000667078, ENST00000667118, ENST00000667147, ENST00000667246, ENST00000667272, ENST00000667735, ENST00000667737, ENST00000668065, ENST00000668216, ENST00000668263, ENST00000668283, ENST00000668338, ENST00000668642, ENST00000668660, ENST00000668973, ENST00000669579, ENST00000669635, ENST00000669916, ENST00000670032, ENST00000670358, ENST00000670428, ENST00000670515, ENST00000670517, ENST00000670764, ENST00000670772, ENST00000670847, ENST00000671268, ENST00000671299, ENST00000671450, ENST00000671529, ENST00000671544, ENST00000769648, ENST00000769649

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000518278 — 7 exons

Exon	Start	End
ENSE00002105015	46846029	46846081
ENSE00002105413	46844189	46844296
ENSE00002115842	46847976	46848100
ENSE00002128823	46840816	46840935
ENSE00002135814	46843350	46843426
ENSE00002704059	46841045	46841126
ENSE00003855079	46848784	46849112

Expression profiles

Bgee: expression breadth ubiquitous, 111 present calls, max score 91.80.

FANTOM5 (CAGE): breadth tissue_specific, TPM avg 0.0203 / max 14.8858, expressed in 5 samples.

FANTOM5 promoters (2 alternative TSS)

Promoter ID	TPM avg	Samples expressed
88742	0.0142	5
88741	0.0061	2

Top tissues by expression

213 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
male germ line stem cell (sensu Vertebrata) in testis	CL:0000089 ∩ UBERON:0000473	91.80	gold quality
left testis	UBERON:0004533	84.07	gold quality
right testis	UBERON:0004534	83.57	gold quality
testis	UBERON:0000473	80.78	gold quality
sperm	CL:0000019	79.18	silver quality
sural nerve	UBERON:0015488	66.27	gold quality
pancreatic ductal cell	CL:0002079	64.76	silver quality
tibialis anterior	UBERON:0001385	64.40	silver quality
bone marrow cell	CL:0002092	63.92	silver quality
ileal mucosa	UBERON:0000331	59.52	silver quality
monocyte	CL:0000576	56.80	gold quality
epithelial cell of pancreas	CL:0000083	55.23	gold quality
deltoid	UBERON:0001476	54.74	gold quality
cardiac muscle of right atrium	UBERON:0003379	54.34	gold quality
left ventricle myocardium	UBERON:0006566	54.23	gold quality
kidney epithelium	UBERON:0004819	53.93	gold quality
upper arm skin	UBERON:0004263	53.52	gold quality
islet of Langerhans	UBERON:0000006	53.04	gold quality
Brodmann (1909) area 9	UBERON:0013540	52.84	gold quality
prefrontal cortex	UBERON:0000451	52.63	gold quality
right lobe of liver	UBERON:0001114	51.51	gold quality
anterior cingulate cortex	UBERON:0009835	50.51	gold quality
myocardium	UBERON:0002349	50.25	gold quality
right frontal lobe	UBERON:0002810	50.24	gold quality
muscle of leg	UBERON:0001383	49.34	gold quality
dorsolateral prefrontal cortex	UBERON:0009834	49.15	gold quality
blood	UBERON:0000178	49.05	gold quality
pancreas	UBERON:0001264	48.96	gold quality
neocortex	UBERON:0001950	48.94	gold quality
frontal cortex	UBERON:0001870	48.86	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 1.

Experiment	Marker?	Max mean expression
E-ANND-3	yes	2.93

Regulation

Is transcription factor: no

Literature-anchored findings (GeneRIF, showing 1)

• A search for ancestor genes within the 8q11.2 region allowed us to identify a gene named BEYLA and to characterize the genomic organization and the expression patterns of this gene [BEYLA] (PMID:15676287)

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.