LINC00301

Summary

LINC00301 (long intergenic non-protein coding RNA 301, HGNC:28603) is a long non-coding RNA gene on chromosome 11q12.2.

Predicted to be located in membrane.

Source: NCBI Gene 283197 — RefSeq curated summary.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:28603
Approved symbol	LINC00301
Name	long intergenic non-protein coding RNA 301
Location	11q12.2
Locus type	RNA, long non-coding
Status	Approved
Aliases	MGC39681
Ensembl gene	ENSG00000293513
Ensembl biotype	lncRNA
Entrez	283197
RNAcentral	URS0000759996 — lncRNA, 864 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 42 — 42 lncRNA

ENST00000320202, ENST00000412599, ENST00000527161, ENST00000532591, ENST00000644084, ENST00000646346, ENST00000646374, ENST00000837577, ENST00000837578, ENST00000837579, ENST00000837580, ENST00000837581, ENST00000837582, ENST00000837583, ENST00000837584, ENST00000837585, ENST00000837586, ENST00000837587, ENST00000837588, ENST00000837589, ENST00000837590, ENST00000837591, ENST00000837592, ENST00000837593, ENST00000837594, ENST00000837595, ENST00000837596, ENST00000837597, ENST00000837598, ENST00000837599, ENST00000837600, ENST00000837601, ENST00000837602, ENST00000837603, ENST00000837604, ENST00000837605, ENST00000837606, ENST00000837607, ENST00000837608, ENST00000837609, ENST00000837610, ENST00000837611

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000320202 — 7 exons

Exon	Start	End
ENSE00001520221	60660722	60660775
ENSE00001520224	60653689	60653783
ENSE00001635980	60686910	60687149
ENSE00001679635	60628289	60628408
ENSE00001741187	60649168	60649310
ENSE00001940360	60621021	60621118
ENSE00004258176	60615726	60615852

Expression profiles

FANTOM5 (CAGE): breadth tissue_specific, TPM avg 0.1268 / max 112.7712, expressed in 4 samples.

FANTOM5 promoters (3 alternative TSS)

Promoter ID	TPM avg	Samples expressed
114482	0.1126	3
114483	0.0116	4
114481	0.0026	2

Top tissues by expression

0 total, by Bgee expression score (0-100, higher = more expressed):

Regulation

Is transcription factor: no

Literature-anchored findings (GeneRIF, showing 1)

• FOXC1-mediated LINC00301 facilitates tumor progression and triggers an immune-suppressing microenvironment in non-small cell lung cancer by regulating the HIF1alpha pathway. (PMID:32878637)

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.