LINC00304

Summary

LINC00304 (long intergenic non-protein coding RNA 304, HGNC:26713) is a long non-coding RNA gene on chromosome 16q24.3.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:26713
Approved symbol	LINC00304
Name	long intergenic non-protein coding RNA 304
Location	16q24.3
Locus type	RNA, long non-coding
Status	Approved
Aliases	FLJ36701
Ensembl gene	ENSG00000180422
Ensembl biotype	lncRNA
Entrez	283860
RNAcentral	URS00001AE523 — lncRNA, 2243 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 3 — 3 lncRNA

ENST00000321214, ENST00000562248, ENST00000565008

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000321214 — 4 exons

Exon	Start	End
ENSE00001241896	89163122	89163675
ENSE00001242269	89159220	89159390
ENSE00001242282	89159708	89159881
ENSE00001311543	89160216	89161559

Expression profiles

Bgee: expression breadth ubiquitous, 147 present calls, max score 83.93.

FANTOM5 (CAGE): breadth tissue_specific, TPM avg 0.3164 / max 201.9835, expressed in 48 samples.

FANTOM5 promoters (1 alternative TSS)

Promoter ID	TPM avg	Samples expressed
155577	0.3164	48

Top tissues by expression

235 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
right hemisphere of cerebellum	UBERON:0014890	83.93	gold quality
cerebellar hemisphere	UBERON:0002245	82.80	gold quality
cerebellar cortex	UBERON:0002129	82.42	gold quality
cerebellum	UBERON:0002037	79.50	gold quality
primordial germ cell in gonad	CL:0000670 ∩ UBERON:0000991	78.86	silver quality
male germ line stem cell (sensu Vertebrata) in testis	CL:0000089 ∩ UBERON:0000473	76.51	gold quality
lower esophagus muscularis layer	UBERON:0035833	66.36	gold quality
cortical plate	UBERON:0005343	66.29	gold quality
lower esophagus	UBERON:0013473	66.26	gold quality
esophagogastric junction muscularis propria	UBERON:0035841	64.48	gold quality
muscle layer of sigmoid colon	UBERON:0035805	64.37	gold quality
left ovary	UBERON:0002119	64.30	gold quality
right ovary	UBERON:0002118	64.07	gold quality
body of uterus	UBERON:0009853	63.75	gold quality
ectocervix	UBERON:0012249	63.61	gold quality
sural nerve	UBERON:0015488	63.12	silver quality
gastrocnemius	UBERON:0001388	63.09	gold quality
left uterine tube	UBERON:0001303	62.83	gold quality
muscle of leg	UBERON:0001383	62.78	gold quality
stromal cell of endometrium	CL:0002255	62.65	gold quality
mucosa of stomach	UBERON:0001199	61.58	gold quality
hindlimb stylopod muscle	UBERON:0004252	61.56	gold quality
spleen	UBERON:0002106	61.16	gold quality
cartilage tissue	UBERON:0002418	60.79	silver quality
endocervix	UBERON:0000458	60.51	gold quality
metanephros cortex	UBERON:0010533	60.26	gold quality
ventricular zone	UBERON:0003053	59.70	gold quality
ovary	UBERON:0000992	59.49	gold quality
tibial nerve	UBERON:0001323	59.27	gold quality
right frontal lobe	UBERON:0002810	58.86	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 0.

Experiment	Marker?	Max mean expression
E-ANND-3	no	1.26

Regulation

Is transcription factor: no

Literature-anchored findings (GeneRIF, showing 1)

• Authors observed higher expression of LINC00304 in PCa cells and samples compared with normal prostate cells and tissues. Functional analysis of LINC00304 showed it was related to regulating cell cycle process, cellular developmental process, and focal adhesion. (PMID:31012142)

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.