LINC00307

Summary

LINC00307 (long intergenic non-protein coding RNA 307, HGNC:16727) is a long non-coding RNA gene on chromosome 21q22.11.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:16727
Approved symbol	LINC00307
Name	long intergenic non-protein coding RNA 307
Location	21q22.11
Locus type	RNA, long non-coding
Status	Approved
Aliases	D21S2091E
Ensembl gene	ENSG00000227342
Ensembl biotype	lncRNA
Entrez	266919
RNAcentral	URS000075B32C — lncRNA, 445 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 1 — 1 lncRNA

ENST00000451410

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000451410 — 3 exons

Exon	Start	End
ENSE00001628879	30209151	30209336
ENSE00001727481	30209738	30209925
ENSE00001778264	30211734	30211783

Expression profiles

Bgee: expression breadth broad, 57 present calls, max score 66.20.

Top tissues by expression

180 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
primordial germ cell in gonad	CL:0000670 ∩ UBERON:0000991	66.20	gold quality
olfactory segment of nasal mucosa	UBERON:0005386	56.94	gold quality
ascending aorta	UBERON:0001496	56.28	gold quality
rectum	UBERON:0001052	54.70	gold quality
Brodmann (1909) area 9	UBERON:0013540	53.15	gold quality
right frontal lobe	UBERON:0002810	52.80	gold quality
gastrocnemius	UBERON:0001388	50.35	gold quality
lower esophagus muscularis layer	UBERON:0035833	50.02	gold quality
muscle layer of sigmoid colon	UBERON:0035805	49.39	gold quality
body of stomach	UBERON:0001161	47.66	gold quality
adult mammalian kidney	UBERON:0000082	47.06	gold quality
body of pancreas	UBERON:0001150	46.78	silver quality
aorta	UBERON:0000947	45.47	gold quality
right lobe of thyroid gland	UBERON:0001119	45.15	gold quality
transverse colon	UBERON:0001157	44.88	gold quality
putamen	UBERON:0001874	44.37	gold quality
esophagogastric junction muscularis propria	UBERON:0035841	44.16	silver quality
large intestine	UBERON:0000059	43.62	gold quality
upper lobe of left lung	UBERON:0008952	43.62	gold quality
kidney	UBERON:0002113	43.60	gold quality
colon	UBERON:0001155	43.58	gold quality
skeletal muscle tissue of rectus abdominis	UBERON:0004511	43.37	gold quality
skin of abdomen	UBERON:0001416	43.21	gold quality
vagina	UBERON:0000996	43.01	silver quality
thyroid gland	UBERON:0002046	42.91	gold quality
esophagus	UBERON:0001043	42.83	silver quality
buccal mucosa cell	CL:0002336	42.78	gold quality
esophagus mucosa	UBERON:0002469	42.76	silver quality
secondary oocyte	CL:0000655	42.57	gold quality
minor salivary gland	UBERON:0001830	42.30	silver quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 0.

Experiment	Marker?	Max mean expression
E-ANND-3	no	0.97

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.