LINC00310

Summary

LINC00310 (long intergenic non-protein coding RNA 310, HGNC:16414) is a long non-coding RNA gene on chromosome 21q22.11.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:16414
Approved symbol	LINC00310
Name	long intergenic non-protein coding RNA 310
Location	21q22.11
Locus type	RNA, long non-coding
Status	Approved
Ensembl gene	ENSG00000227456
Ensembl biotype	lncRNA
Entrez	114036
RNAcentral	URS000075E93F — lncRNA, 1269 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 17 — 17 lncRNA

ENST00000416145, ENST00000419881, ENST00000427022, ENST00000428914, ENST00000430922, ENST00000609062, ENST00000609947, ENST00000619549, ENST00000630751, ENST00000652428, ENST00000715812, ENST00000807094, ENST00000807095, ENST00000807096, ENST00000807097, ENST00000807098, ENST00000807099

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000416145 — 2 exons

Exon	Start	End
ENSE00001747668	34180744	34180793
ENSE00001797561	34188217	34188562

Expression profiles

Bgee: expression breadth ubiquitous, 159 present calls, max score 88.23.

FANTOM5 (CAGE): breadth tissue_specific, TPM avg 0.1807 / max 14.9456, expressed in 92 samples.

FANTOM5 promoters (2 alternative TSS)

Promoter ID	TPM avg	Samples expressed
188920	0.1519	84
188921	0.0287	12

Top tissues by expression

248 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
bone marrow cell	CL:0002092	88.23	gold quality
hindlimb stylopod muscle	UBERON:0004252	83.74	gold quality
popliteal artery	UBERON:0002250	82.68	gold quality
tibial artery	UBERON:0007610	82.65	gold quality
right coronary artery	UBERON:0001625	81.84	gold quality
left coronary artery	UBERON:0001626	81.42	gold quality
aorta	UBERON:0000947	80.32	gold quality
coronary artery	UBERON:0001621	80.00	gold quality
descending thoracic aorta	UBERON:0002345	78.59	gold quality
vastus lateralis	UBERON:0001379	78.32	silver quality
skeletal muscle tissue of biceps brachii	UBERON:0004502	77.66	silver quality
thoracic aorta	UBERON:0001515	77.61	gold quality
ascending aorta	UBERON:0001496	77.53	gold quality
calcaneal tendon	UBERON:0003701	76.22	gold quality
skeletal muscle tissue of rectus abdominis	UBERON:0004511	75.68	silver quality
biceps brachii	UBERON:0001507	75.55	silver quality
skeletal muscle tissue	UBERON:0001134	74.80	gold quality
primordial germ cell in gonad	CL:0000670 ∩ UBERON:0000991	73.55	gold quality
colonic epithelium	UBERON:0000397	71.96	gold quality
muscle of leg	UBERON:0001383	71.46	gold quality
gastrocnemius	UBERON:0001388	69.58	gold quality
right lobe of thyroid gland	UBERON:0001119	69.48	gold quality
subcutaneous adipose tissue	UBERON:0002190	68.79	gold quality
tibial nerve	UBERON:0001323	68.71	gold quality
left lobe of thyroid gland	UBERON:0001120	68.51	gold quality
thyroid gland	UBERON:0002046	68.42	gold quality
sural nerve	UBERON:0015488	67.39	gold quality
deltoid	UBERON:0001476	66.80	silver quality
adipose tissue	UBERON:0001013	65.80	gold quality
metanephros cortex	UBERON:0010533	65.67	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 0.

Experiment	Marker?	Max mean expression
E-ANND-3	no	3.37

Regulation

Is transcription factor: no

Literature-anchored findings (GeneRIF, showing 2)

• Long non-coding RNA LINC00310 promoted cell proliferation by regulating c-Myc expression in vitro. (PMID:29993199)
• [Role of LINC00310 in the glycidyl methacrylate-induced malignant transformation of human bronchial epithelial cell]. (PMID:33070810)

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.