LINC00323

Summary

LINC00323 (long intergenic non-protein coding RNA 323, HGNC:19720) is a long non-coding RNA gene on chromosome 21q22.2.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:19720
Approved symbol	LINC00323
Name	long intergenic non-protein coding RNA 323
Location	21q22.2
Locus type	RNA, long non-coding
Status	Approved
Aliases	PRED42, FLJ37173
Ensembl gene	ENSG00000226496
Ensembl biotype	lncRNA
Entrez	284835
RNAcentral	URS000075E532 — lncRNA, 2019 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 10 — 10 lncRNA

ENST00000435493, ENST00000441268, ENST00000446910, ENST00000654244, ENST00000660097, ENST00000836835, ENST00000836836, ENST00000836837, ENST00000836838, ENST00000836839

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000435493 — 4 exons

Exon	Start	End
ENSE00001658161	41147349	41147499
ENSE00004256695	41141536	41143415
ENSE00004256701	41147962	41148126
ENSE00004256706	41168543	41168796

Expression profiles

Bgee: expression breadth ubiquitous, 162 present calls, max score 93.77.

FANTOM5 (CAGE): breadth tissue_specific, TPM avg 0.2954 / max 116.7676, expressed in 45 samples.

FANTOM5 promoters (3 alternative TSS)

Promoter ID	TPM avg	Samples expressed
190527	0.2513	39
190526	0.0271	13
190528	0.0169	6

Top tissues by expression

237 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
C1 segment of cervical spinal cord	UBERON:0006469	93.77	gold quality
spinal cord	UBERON:0002240	92.72	gold quality
medial globus pallidus	UBERON:0002477	75.51	gold quality
buccal mucosa cell	CL:0002336	75.42	gold quality
cortical plate	UBERON:0005343	74.36	gold quality
oviduct epithelium	UBERON:0004804	73.70	gold quality
substantia nigra	UBERON:0002038	73.64	gold quality
pons	UBERON:0000988	73.31	gold quality
midbrain	UBERON:0001891	71.84	gold quality
endothelial cell	CL:0000115	70.01	gold quality
subthalamic nucleus	UBERON:0001906	69.57	gold quality
globus pallidus	UBERON:0001875	69.37	gold quality
right uterine tube	UBERON:0001302	68.70	gold quality
medulla oblongata	UBERON:0001896	67.59	gold quality
inferior vagus X ganglion	UBERON:0005363	66.67	gold quality
hindlimb stylopod muscle	UBERON:0004252	66.58	gold quality
fallopian tube	UBERON:0003889	62.61	gold quality
prefrontal cortex	UBERON:0000451	61.38	gold quality
metanephros cortex	UBERON:0010533	61.21	gold quality
ventricular zone	UBERON:0003053	60.98	gold quality
hypothalamus	UBERON:0001898	60.80	gold quality
tibial nerve	UBERON:0001323	59.77	gold quality
superior vestibular nucleus	UBERON:0007227	59.36	gold quality
cortex of kidney	UBERON:0001225	59.15	gold quality
corpus callosum	UBERON:0002336	59.06	gold quality
smooth muscle tissue	UBERON:0001135	59.00	gold quality
adult mammalian kidney	UBERON:0000082	58.63	gold quality
right coronary artery	UBERON:0001625	58.47	gold quality
thoracic aorta	UBERON:0001515	58.42	gold quality
popliteal artery	UBERON:0002250	58.26	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 0.

Experiment	Marker?	Max mean expression
E-ANND-3	no	1.55

Regulation

Is transcription factor: no

Literature-anchored findings (GeneRIF, showing 1)

• Increased expression of LINC00323 correlates with tumor progression and poor prognosis of gastric cancer. (PMID:37545221)

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.