LINC00333

Summary

LINC00333 (long intergenic non-protein coding RNA 333, HGNC:42050) is a long non-coding RNA gene on chromosome 13q31.1.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:42050
Approved symbol	LINC00333
Name	long intergenic non-protein coding RNA 333
Location	13q31.1
Locus type	RNA, long non-coding
Status	Approved
Ensembl gene	ENSG00000233349
Ensembl biotype	lncRNA
Entrez	100874128
RNAcentral	URS000075B143 — lncRNA, 812 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 1 — 1 lncRNA

ENST00000446314

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000446314 — 3 exons

Exon	Start	End
ENSE00001662921	84562792	84563236
ENSE00001679621	84562364	84562463
ENSE00001766814	84562609	84562676

Expression profiles

Bgee: expression breadth broad, 66 present calls, max score 93.58.

Top tissues by expression

66 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
male germ line stem cell (sensu Vertebrata) in testis	CL:0000089 ∩ UBERON:0000473	93.58	gold quality
skeletal muscle tissue	UBERON:0001134	65.46	gold quality
right uterine tube	UBERON:0001302	58.45	gold quality
monocyte	CL:0000576	58.01	gold quality
fallopian tube	UBERON:0003889	57.69	gold quality
islet of Langerhans	UBERON:0000006	51.80	gold quality
blood	UBERON:0000178	50.96	silver quality
small intestine	UBERON:0002108	50.85	gold quality
prefrontal cortex	UBERON:0000451	50.41	gold quality
lymph node	UBERON:0000029	50.05	gold quality
superior frontal gyrus	UBERON:0002661	49.84	gold quality
adult mammalian kidney	UBERON:0000082	48.40	silver quality
body of stomach	UBERON:0001161	46.08	gold quality
body of pancreas	UBERON:0001150	45.71	gold quality
frontal cortex	UBERON:0001870	45.68	gold quality
lung	UBERON:0002048	44.98	gold quality
ascending aorta	UBERON:0001496	44.30	gold quality
thoracic aorta	UBERON:0001515	44.07	gold quality
anterior cingulate cortex	UBERON:0009835	43.97	silver quality
tonsil	UBERON:0002372	43.87	silver quality
lower esophagus muscularis layer	UBERON:0035833	43.45	silver quality
corpus callosum	UBERON:0002336	43.36	silver quality
gastrocnemius	UBERON:0001388	43.32	silver quality
lower esophagus	UBERON:0013473	43.30	silver quality
tibial artery	UBERON:0007610	43.00	silver quality
esophagus	UBERON:0001043	42.75	gold quality
thyroid gland	UBERON:0002046	42.40	gold quality
dorsolateral prefrontal cortex	UBERON:0009834	42.35	silver quality
right adrenal gland	UBERON:0001233	42.28	silver quality
right adrenal gland cortex	UBERON:0035827	42.26	silver quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 0.

Experiment	Marker?	Max mean expression
E-ANND-3	no	1.47

Regulation

Is transcription factor: no

Literature-anchored findings (GeneRIF, showing 1)

• Ultraconserved element uc.333 increases insulin sensitivity by binding to miR-223. (PMID:32303004)

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.