LINC00334

Summary

LINC00334 (long intergenic non-protein coding RNA 334, HGNC:16425) is a long non-coding RNA gene on chromosome 21q22.3.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:16425
Approved symbol	LINC00334
Name	long intergenic non-protein coding RNA 334
Location	21q22.3
Locus type	RNA, long non-coding
Status	Approved
Ensembl gene	ENSG00000182586
Ensembl biotype	lncRNA
Entrez	114042
RNAcentral	URS0000A765AF — lncRNA, 542 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 13 — 13 lncRNA

ENST00000328344, ENST00000584169, ENST00000638500, ENST00000660971, ENST00000665973, ENST00000670852, ENST00000670960, ENST00000757334, ENST00000757335, ENST00000757336, ENST00000757337, ENST00000757338, ENST00000757339

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000328344 — 3 exons

Exon	Start	End
ENSE00001330272	45258451	45258730
ENSE00001542589	45243532	45243626
ENSE00001542591	45234352	45234506

Expression profiles

Bgee: expression breadth ubiquitous, 152 present calls, max score 88.59.

FANTOM5 (CAGE): breadth tissue_specific, TPM avg 0.0622 / max 5.7711, expressed in 27 samples.

FANTOM5 promoters (1 alternative TSS)

Promoter ID	TPM avg	Samples expressed
189539	0.0622	27

Top tissues by expression

240 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
primordial germ cell in gonad	CL:0000670 ∩ UBERON:0000991	88.59	gold quality
male germ line stem cell (sensu Vertebrata) in testis	CL:0000089 ∩ UBERON:0000473	82.90	gold quality
bone marrow cell	CL:0002092	67.39	silver quality
cortical plate	UBERON:0005343	65.74	gold quality
stromal cell of endometrium	CL:0002255	64.39	gold quality
ventricular zone	UBERON:0003053	63.73	gold quality
adenohypophysis	UBERON:0002196	62.88	gold quality
granulocyte	CL:0000094	61.47	gold quality
pituitary gland	UBERON:0000007	61.39	gold quality
hypothalamus	UBERON:0001898	61.31	gold quality
cerebellar cortex	UBERON:0002129	61.13	gold quality
cerebellar hemisphere	UBERON:0002245	61.08	gold quality
sural nerve	UBERON:0015488	60.65	silver quality
cerebellar vermis	UBERON:0004720	60.43	gold quality
ganglionic eminence	UBERON:0004023	60.10	gold quality
right hemisphere of cerebellum	UBERON:0014890	59.98	gold quality
buccal mucosa cell	CL:0002336	59.91	gold quality
cerebellum	UBERON:0002037	59.77	gold quality
left testis	UBERON:0004533	58.45	gold quality
hindlimb stylopod muscle	UBERON:0004252	58.36	gold quality
muscle layer of sigmoid colon	UBERON:0035805	57.85	gold quality
anterior cingulate cortex	UBERON:0009835	57.74	gold quality
right testis	UBERON:0004534	57.62	gold quality
left uterine tube	UBERON:0001303	57.07	gold quality
right frontal lobe	UBERON:0002810	57.05	gold quality
testis	UBERON:0000473	57.03	gold quality
Brodmann (1909) area 9	UBERON:0013540	56.29	gold quality
olfactory segment of nasal mucosa	UBERON:0005386	55.63	gold quality
amygdala	UBERON:0001876	55.44	gold quality
muscle of leg	UBERON:0001383	54.79	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 0.

Experiment	Marker?	Max mean expression
E-ANND-3	no	1.12

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.