LINC00343
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Summary
LINC00343 (long intergenic non-protein coding RNA 343, HGNC:42500) is a long non-coding RNA gene on chromosome 13q33.2.
At a glance
- Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).
Identifiers
Gene identifiers
| Field | Value |
|---|---|
| HGNC ID | HGNC:42500 |
| Approved symbol | LINC00343 |
| Name | long intergenic non-protein coding RNA 343 |
| Location | 13q33.2 |
| Locus type | RNA, long non-coding |
| Status | Approved |
| Ensembl gene | ENSG00000226620 |
| Ensembl biotype | lncRNA |
| Entrez | 144920 |
| RNAcentral | URS000075B616 — lncRNA, 1276 nt, 1 organism(s) |
Gene structure
Transcript identifiers
Ensembl transcripts: 145 — 144 lncRNA, 1 retained_intron
ENST00000414368, ENST00000415294, ENST00000454555, ENST00000596398, ENST00000598229, ENST00000598478, ENST00000599179, ENST00000599264, ENST00000601607, ENST00000608220, ENST00000608426, ENST00000608624, ENST00000653082, ENST00000653178, ENST00000653504, ENST00000653600, ENST00000654086, ENST00000654132, ENST00000654352, ENST00000654904, ENST00000654919, ENST00000655062, ENST00000655173, ENST00000655201, ENST00000655206, ENST00000655448, ENST00000655625, ENST00000655741, ENST00000656267, ENST00000656290, ENST00000656479, ENST00000656539, ENST00000656615, ENST00000656646, ENST00000656920, ENST00000657324, ENST00000657599, ENST00000657690, ENST00000658024, ENST00000658095, ENST00000658151, ENST00000658169, ENST00000658308, ENST00000658692, ENST00000658711, ENST00000659016, ENST00000659165, ENST00000659258, ENST00000659496, ENST00000659909, ENST00000660236, ENST00000660294, ENST00000660560, ENST00000660821, ENST00000660976, ENST00000661079, ENST00000661301, ENST00000661782, ENST00000661817, ENST00000661872, ENST00000661976, ENST00000662500, ENST00000662776, ENST00000663045, ENST00000663194, ENST00000663287, ENST00000663594, ENST00000663744, ENST00000663761, ENST00000663969, ENST00000664090, ENST00000664140, ENST00000664201, ENST00000664522, ENST00000664695, ENST00000664796, ENST00000665309, ENST00000665747, ENST00000666040, ENST00000666322, ENST00000666696, ENST00000666723, ENST00000666948, ENST00000667106, ENST00000667217, ENST00000667429, ENST00000667492, ENST00000667534, ENST00000667582, ENST00000667685, ENST00000667987, ENST00000668080, ENST00000668272, ENST00000668279, ENST00000668362, ENST00000668396, ENST00000668581, ENST00000668939, ENST00000668966, ENST00000669035, ENST00000669144, ENST00000669264, ENST00000669497, ENST00000669507, ENST00000669540, ENST00000669655, ENST00000669675, ENST00000669706, ENST00000669807, ENST00000669840, ENST00000669886, ENST00000669887, ENST00000669959, ENST00000670114, ENST00000670303, ENST00000670308, ENST00000670429, ENST00000670430, ENST00000670433, ENST00000670530, ENST00000670546, ENST00000670555, ENST00000670771, ENST00000670821, ENST00000670977, ENST00000671026, ENST00000671053, ENST00000671060, ENST00000671402, ENST00000671516, ENST00000671561, ENST00000831894, ENST00000831895, ENST00000831896, ENST00000831897, ENST00000831898, ENST00000831899, ENST00000831900, ENST00000831901, ENST00000831902, ENST00000831903, ENST00000831904, ENST00000831905, ENST00000831906, ENST00000831907
RefSeq mRNA: 0 — MANE Select: None
Canonical transcript exons
ENST00000414368 — 3 exons
| Exon | Start | End |
|---|---|---|
| ENSE00001655568 | 105730315 | 105730458 |
| ENSE00003704172 | 105729501 | 105729959 |
| ENSE00003710041 | 105731448 | 105731708 |
Expression profiles
Bgee: expression breadth broad, 85 present calls, max score 87.59.
FANTOM5 (CAGE): breadth tissue_specific, TPM avg 0.0322 / max 25.6620, expressed in 3 samples.
FANTOM5 promoters (1 alternative TSS)
| Promoter ID | TPM avg | Samples expressed |
|---|---|---|
| 135952 | 0.0322 | 3 |
Top tissues by expression
189 total, by Bgee expression score (0-100, higher = more expressed):
| Tissue | Anatomy ID | Expression score | Quality |
|---|---|---|---|
| left testis | UBERON:0004533 | 87.59 | gold quality |
| right testis | UBERON:0004534 | 86.10 | gold quality |
| testis | UBERON:0000473 | 84.08 | gold quality |
| male germ line stem cell (sensu Vertebrata) in testis | CL:0000089 ∩ UBERON:0000473 | 82.81 | gold quality |
| sural nerve | UBERON:0015488 | 79.01 | silver quality |
| primordial germ cell in gonad | CL:0000670 ∩ UBERON:0000991 | 78.58 | gold quality |
| colonic epithelium | UBERON:0000397 | 72.32 | gold quality |
| bone marrow cell | CL:0002092 | 70.90 | silver quality |
| cortical plate | UBERON:0005343 | 68.60 | gold quality |
| prefrontal cortex | UBERON:0000451 | 66.85 | gold quality |
| ventricular zone | UBERON:0003053 | 64.56 | gold quality |
| Brodmann (1909) area 9 | UBERON:0013540 | 62.30 | gold quality |
| ganglionic eminence | UBERON:0004023 | 61.62 | gold quality |
| frontal cortex | UBERON:0001870 | 58.67 | gold quality |
| dorsolateral prefrontal cortex | UBERON:0009834 | 58.41 | gold quality |
| neocortex | UBERON:0001950 | 57.78 | gold quality |
| tonsil | UBERON:0002372 | 57.19 | silver quality |
| anterior cingulate cortex | UBERON:0009835 | 56.87 | gold quality |
| hindlimb stylopod muscle | UBERON:0004252 | 56.86 | gold quality |
| uterine cervix | UBERON:0000002 | 56.78 | silver quality |
| right frontal lobe | UBERON:0002810 | 56.75 | gold quality |
| cerebral cortex | UBERON:0000956 | 54.88 | gold quality |
| monocyte | CL:0000576 | 54.43 | gold quality |
| adrenal gland | UBERON:0002369 | 53.98 | gold quality |
| right lobe of liver | UBERON:0001114 | 52.50 | gold quality |
| forebrain | UBERON:0001890 | 52.09 | gold quality |
| cerebellar hemisphere | UBERON:0002245 | 52.04 | gold quality |
| right hemisphere of cerebellum | UBERON:0014890 | 51.87 | gold quality |
| metanephros cortex | UBERON:0010533 | 51.76 | gold quality |
| muscle of leg | UBERON:0001383 | 51.55 | gold quality |
Single-cell (SCXA)
Detected in 1 experiment(s), a significant marker in 1.
| Experiment | Marker? | Max mean expression |
|---|---|---|
| E-ANND-3 | yes | 5.22 |
Regulation
Is transcription factor: no
Cross-species orthologs
0 orthologs
Protein
Non-coding RNA — no protein product; not a drug target.
Function
No curated pathway, Gene-Ontology, or interaction data.
Disease & clinical
No curated disease, variant, or cancer-driver associations.
Drugs & pharmacology
No drug or pharmacology data — not an established drug target.
Related Atlas pages
- Disease cohort memberships (association, not causation — diseases whose associated-gene cohort lists this gene; a subset are also under Associated diseases): diabetic macular edema