LINC00347
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Summary
LINC00347 (long intergenic non-protein coding RNA 347, HGNC:27890) is a long non-coding RNA gene on chromosome 13q22.1.
At a glance
- Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).
Identifiers
Gene identifiers
| Field | Value |
|---|---|
| HGNC ID | HGNC:27890 |
| Approved symbol | LINC00347 |
| Name | long intergenic non-protein coding RNA 347 |
| Location | 13q22.1 |
| Locus type | RNA, long non-coding |
| Status | Approved |
| Ensembl gene | ENSG00000236678 |
| Ensembl biotype | lncRNA |
| Entrez | 338864 |
| RNAcentral | URS000075A60E — lncRNA, 2105 nt, 1 organism(s) |
Gene structure
Transcript identifiers
Ensembl transcripts: 8 — 8 lncRNA
ENST00000451336, ENST00000594461, ENST00000595711, ENST00000596240, ENST00000597518, ENST00000600832, ENST00000601480, ENST00000664176
RefSeq mRNA: 0 — MANE Select: None
Canonical transcript exons
ENST00000451336 — 3 exons
| Exon | Start | End |
|---|---|---|
| ENSE00001599137 | 74555225 | 74555738 |
| ENSE00001630405 | 74552843 | 74552903 |
| ENSE00001679620 | 74554657 | 74554760 |
Expression profiles
Bgee: expression breadth ubiquitous, 114 present calls, max score 86.23.
FANTOM5 (CAGE): breadth tissue_specific, TPM avg 0.0287 / max 32.4781, expressed in 3 samples.
FANTOM5 promoters (1 alternative TSS)
| Promoter ID | TPM avg | Samples expressed |
|---|---|---|
| 135391 | 0.0287 | 3 |
Top tissues by expression
114 total, by Bgee expression score (0-100, higher = more expressed):
| Tissue | Anatomy ID | Expression score | Quality |
|---|---|---|---|
| left testis | UBERON:0004533 | 86.23 | gold quality |
| testis | UBERON:0000473 | 85.91 | gold quality |
| right testis | UBERON:0004534 | 85.53 | gold quality |
| primordial germ cell in gonad | CL:0000670 ∩ UBERON:0000991 | 68.12 | gold quality |
| stromal cell of endometrium | CL:0002255 | 58.65 | gold quality |
| endometrium | UBERON:0001295 | 56.65 | gold quality |
| calcaneal tendon | UBERON:0003701 | 55.30 | gold quality |
| monocyte | CL:0000576 | 55.19 | gold quality |
| bone marrow | UBERON:0002371 | 55.14 | gold quality |
| hindlimb stylopod muscle | UBERON:0004252 | 54.49 | gold quality |
| liver | UBERON:0002107 | 54.38 | gold quality |
| blood | UBERON:0000178 | 53.04 | gold quality |
| apex of heart | UBERON:0002098 | 52.22 | gold quality |
| lymph node | UBERON:0000029 | 52.01 | gold quality |
| superior frontal gyrus | UBERON:0002661 | 50.82 | gold quality |
| corpus callosum | UBERON:0002336 | 50.49 | silver quality |
| islet of Langerhans | UBERON:0000006 | 50.02 | gold quality |
| adrenal tissue | UBERON:0018303 | 49.89 | gold quality |
| prefrontal cortex | UBERON:0000451 | 49.50 | gold quality |
| gall bladder | UBERON:0002110 | 49.45 | gold quality |
| placenta | UBERON:0001987 | 49.34 | gold quality |
| right lobe of liver | UBERON:0001114 | 49.31 | gold quality |
| vermiform appendix | UBERON:0001154 | 48.62 | gold quality |
| primary visual cortex | UBERON:0002436 | 48.61 | gold quality |
| myometrium | UBERON:0001296 | 48.44 | gold quality |
| kidney | UBERON:0002113 | 48.30 | silver quality |
| multicellular organism | UBERON:0000468 | 47.87 | gold quality |
| muscle of leg | UBERON:0001383 | 47.51 | gold quality |
| cortex of kidney | UBERON:0001225 | 47.49 | silver quality |
| olfactory segment of nasal mucosa | UBERON:0005386 | 47.29 | gold quality |
Single-cell (SCXA)
Detected in 1 experiment(s), a significant marker in 1.
| Experiment | Marker? | Max mean expression |
|---|---|---|
| E-ANND-3 | yes | 3.60 |
Regulation
Is transcription factor: no
Cross-species orthologs
0 orthologs
Protein
Non-coding RNA — no protein product; not a drug target.
Function
No curated pathway, Gene-Ontology, or interaction data.
Disease & clinical
No curated disease, variant, or cancer-driver associations.
Drugs & pharmacology
No drug or pharmacology data — not an established drug target.
Related Atlas pages
- Disease cohort memberships (association, not causation — diseases whose associated-gene cohort lists this gene; a subset are also under Associated diseases): ataxia, intention tremor, and hypotonia syndrome, childhood-onset, Waardenburg syndrome type 4A