LINC00351

Summary

LINC00351 (long intergenic non-protein coding RNA 351, HGNC:42669) is a long non-coding RNA gene on chromosome 13q31.1.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:42669
Approved symbol	LINC00351
Name	long intergenic non-protein coding RNA 351
Location	13q31.1
Locus type	RNA, long non-coding
Status	Approved
Ensembl gene	ENSG00000226317
Ensembl biotype	lncRNA
Entrez	100874137
RNAcentral	URS000075EF2D — lncRNA, 1001 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 2 — 2 lncRNA

ENST00000424926, ENST00000655792

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000424926 — 4 exons

Exon	Start	End
ENSE00001666351	85363601	85364095
ENSE00001739327	85542238	85542330
ENSE00001796734	85544376	85544570
ENSE00001805819	85533076	85533203

Expression profiles

Bgee: expression breadth broad, 35 present calls, max score 87.18.

FANTOM5 (CAGE): breadth tissue_specific, TPM avg 0.0824 / max 34.3091, expressed in 31 samples.

FANTOM5 promoters (1 alternative TSS)

Promoter ID	TPM avg	Samples expressed
135592	0.0824	31

Top tissues by expression

35 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
primordial germ cell in gonad	CL:0000670 ∩ UBERON:0000991	87.18	gold quality
male germ line stem cell (sensu Vertebrata) in testis	CL:0000089 ∩ UBERON:0000473	77.68	gold quality
muscle tissue	UBERON:0002385	68.55	gold quality
urinary bladder	UBERON:0001255	63.71	gold quality
monocyte	CL:0000576	51.72	silver quality
prefrontal cortex	UBERON:0000451	51.71	gold quality
blood	UBERON:0000178	50.13	silver quality
adipose tissue	UBERON:0001013	49.17	gold quality
cortex of kidney	UBERON:0001225	48.21	silver quality
heart left ventricle	UBERON:0002084	47.03	gold quality
putamen	UBERON:0001874	44.88	gold quality
corpus callosum	UBERON:0002336	44.64	silver quality
testis	UBERON:0000473	44.30	gold quality
multicellular organism	UBERON:0000468	43.80	gold quality
left testis	UBERON:0004533	43.28	gold quality
gastrocnemius	UBERON:0001388	42.39	silver quality
subcutaneous adipose tissue	UBERON:0002190	42.25	silver quality
right testis	UBERON:0004534	41.80	gold quality
left ovary	UBERON:0002119	41.13	silver quality
tibial artery	UBERON:0007610	41.08	silver quality
Ammon’s horn	UBERON:0001954	40.41	silver quality
right ovary	UBERON:0002118	40.17	silver quality
right atrium auricular region	UBERON:0006631	39.76	silver quality
caudate nucleus	UBERON:0001873	39.23	silver quality
amygdala	UBERON:0001876	38.64	silver quality
C1 segment of cervical spinal cord	UBERON:0006469	38.26	silver quality
substantia nigra	UBERON:0002038	38.09	silver quality
muscle layer of sigmoid colon	UBERON:0035805	37.74	silver quality
pituitary gland	UBERON:0000007	37.68	silver quality
hypothalamus	UBERON:0001898	37.58	silver quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 0.

Experiment	Marker?	Max mean expression
E-ANND-3	no	1.80

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.