LINC00352

Summary

LINC00352 (long intergenic non-protein coding RNA 352, HGNC:42670) is a long non-coding RNA gene on chromosome 13q12.12.

Predicted to be involved in SRP-dependent cotranslational protein targeting to membrane, signal sequence recognition. Predicted to be part of signal recognition particle, endoplasmic reticulum targeting.

Source: NCBI Gene 100874138 — RefSeq curated summary.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:42670
Approved symbol	LINC00352
Name	long intergenic non-protein coding RNA 352
Location	13q12.12
Locus type	RNA, long non-coding
Status	Approved
Ensembl gene	ENSG00000227893
Ensembl biotype	lncRNA
Entrez	100874138
RNAcentral	URS000034FE56 — lncRNA, 552 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 1 — 1 lncRNA

ENST00000425800

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000425800 — 2 exons

Exon	Start	End
ENSE00001611282	23498796	23498842
ENSE00001674399	23502370	23502874

Expression profiles

Bgee: expression breadth broad, 95 present calls, max score 82.35.

Top tissues by expression

95 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
male germ line stem cell (sensu Vertebrata) in testis	CL:0000089 ∩ UBERON:0000473	82.35	gold quality
testis	UBERON:0000473	68.58	gold quality
ventricular zone	UBERON:0003053	65.18	gold quality
cortical plate	UBERON:0005343	64.30	gold quality
bone marrow	UBERON:0002371	60.33	gold quality
primordial germ cell in gonad	CL:0000670 ∩ UBERON:0000991	57.04	gold quality
hindlimb stylopod muscle	UBERON:0004252	55.59	gold quality
monocyte	CL:0000576	55.22	gold quality
lymph node	UBERON:0000029	53.86	gold quality
islet of Langerhans	UBERON:0000006	53.59	gold quality
blood	UBERON:0000178	53.48	gold quality
liver	UBERON:0002107	52.76	gold quality
descending thoracic aorta	UBERON:0002345	50.60	gold quality
stromal cell of endometrium	CL:0002255	50.55	silver quality
olfactory segment of nasal mucosa	UBERON:0005386	50.55	gold quality
superior frontal gyrus	UBERON:0002661	50.45	gold quality
prefrontal cortex	UBERON:0000451	50.37	gold quality
muscle of leg	UBERON:0001383	50.01	gold quality
gastrocnemius	UBERON:0001388	49.62	gold quality
Brodmann (1909) area 9	UBERON:0013540	49.15	silver quality
right lobe of liver	UBERON:0001114	48.51	gold quality
tonsil	UBERON:0002372	48.11	gold quality
right lobe of thyroid gland	UBERON:0001119	47.63	gold quality
heart left ventricle	UBERON:0002084	47.37	gold quality
granulocyte	CL:0000094	47.30	silver quality
vermiform appendix	UBERON:0001154	46.79	gold quality
ovary	UBERON:0000992	46.50	silver quality
adult mammalian kidney	UBERON:0000082	46.44	silver quality
multicellular organism	UBERON:0000468	45.45	gold quality
lung	UBERON:0002048	45.07	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 0.

Experiment	Marker?	Max mean expression
E-ANND-3	no	2.13

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.