LINC00354

Summary

LINC00354 (long intergenic non-protein coding RNA 354, HGNC:42672) is a long non-coding RNA gene on chromosome 13q34.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:42672
Approved symbol	LINC00354
Name	long intergenic non-protein coding RNA 354
Location	13q34
Locus type	RNA, long non-coding
Status	Approved
Ensembl gene	ENSG00000226903
Ensembl biotype	lncRNA
Entrez	101928616
RNAcentral	URS000075EDC8 — lncRNA, 443 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 24 — 24 lncRNA

ENST00000412119, ENST00000440860, ENST00000655071, ENST00000655663, ENST00000661311, ENST00000662993, ENST00000663211, ENST00000664504, ENST00000668961, ENST00000670406, ENST00000670855, ENST00000700859, ENST00000817496, ENST00000817500, ENST00000817503, ENST00000817505, ENST00000817507, ENST00000817509, ENST00000817511, ENST00000817512, ENST00000817514, ENST00000817515, ENST00000817516, ENST00000817517

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000412119 — 2 exons

Exon	Start	End
ENSE00001675414	111900686	111900936
ENSE00001724879	111899988	111900083

Expression profiles

Bgee: expression breadth broad, 93 present calls, max score 74.66.

FANTOM5 (CAGE): breadth tissue_specific, TPM avg 0.1346 / max 22.5542, expressed in 80 samples.

FANTOM5 promoters (2 alternative TSS)

Promoter ID	TPM avg	Samples expressed
136123	0.0758	36
136122	0.0588	36

Top tissues by expression

195 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
sural nerve	UBERON:0015488	74.66	gold quality
male germ line stem cell (sensu Vertebrata) in testis	CL:0000089 ∩ UBERON:0000473	74.06	silver quality
left testis	UBERON:0004533	73.26	gold quality
right testis	UBERON:0004534	72.83	gold quality
testis	UBERON:0000473	70.90	gold quality
secondary oocyte	CL:0000655	67.18	silver quality
ventricular zone	UBERON:0003053	66.04	gold quality
ganglionic eminence	UBERON:0004023	61.13	gold quality
monocyte	CL:0000576	58.47	gold quality
prefrontal cortex	UBERON:0000451	58.28	gold quality
nucleus accumbens	UBERON:0001882	57.09	gold quality
cortical plate	UBERON:0005343	54.88	silver quality
tonsil	UBERON:0002372	54.01	gold quality
caudate nucleus	UBERON:0001873	53.39	gold quality
anterior cingulate cortex	UBERON:0009835	52.99	gold quality
adult organism	UBERON:0007023	52.62	gold quality
calcaneal tendon	UBERON:0003701	52.43	silver quality
muscle of leg	UBERON:0001383	52.40	gold quality
neocortex	UBERON:0001950	52.19	gold quality
frontal cortex	UBERON:0001870	52.18	gold quality
right frontal lobe	UBERON:0002810	51.53	gold quality
putamen	UBERON:0001874	51.47	gold quality
amygdala	UBERON:0001876	51.43	gold quality
Brodmann (1909) area 9	UBERON:0013540	51.14	gold quality
gall bladder	UBERON:0002110	51.05	gold quality
body of pancreas	UBERON:0001150	50.97	gold quality
primordial germ cell in gonad	CL:0000670 ∩ UBERON:0000991	50.77	silver quality
dorsolateral prefrontal cortex	UBERON:0009834	50.65	gold quality
buccal mucosa cell	CL:0002336	50.10	gold quality
gastrocnemius	UBERON:0001388	49.98	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 0.

Experiment	Marker?	Max mean expression
E-ANND-3	no	0.33

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.