LINC00374

Summary

LINC00374 (long intergenic non-protein coding RNA 374, HGNC:42698) is a long non-coding RNA gene on chromosome 13q21.1.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:42698
Approved symbol	LINC00374
Name	long intergenic non-protein coding RNA 374
Location	13q21.1
Locus type	RNA, long non-coding
Status	Approved
Ensembl gene	ENSG00000232954
Ensembl biotype	lncRNA
Entrez	106144531
RNAcentral	URS00000D11E0 — lncRNA, 800 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 1 — 1 lncRNA

ENST00000454780

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000454780 — 7 exons

Exon	Start	End
ENSE00001639280	58227557	58227616
ENSE00001642146	58215626	58215683
ENSE00001649727	58221866	58221928
ENSE00001689170	58229138	58229210
ENSE00001701736	58232835	58233117
ENSE00001739829	58221137	58221268
ENSE00001802392	58211697	58211827

Expression profiles

Bgee: expression breadth broad, 30 present calls, max score 86.21.

Top tissues by expression

30 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
male germ line stem cell (sensu Vertebrata) in testis	CL:0000089 ∩ UBERON:0000473	86.21	gold quality
muscle tissue	UBERON:0002385	63.50	silver quality
sural nerve	UBERON:0015488	60.62	silver quality
blood	UBERON:0000178	53.49	gold quality
monocyte	CL:0000576	52.53	gold quality
prefrontal cortex	UBERON:0000451	51.12	gold quality
islet of Langerhans	UBERON:0000006	47.31	gold quality
apex of heart	UBERON:0002098	46.71	gold quality
heart	UBERON:0000948	45.60	gold quality
heart left ventricle	UBERON:0002084	45.52	silver quality
Ammon’s horn	UBERON:0001954	45.17	gold quality
substantia nigra	UBERON:0002038	44.03	gold quality
right atrium auricular region	UBERON:0006631	43.58	silver quality
thoracic mammary gland	UBERON:0005200	43.25	silver quality
Brodmann (1909) area 9	UBERON:0013540	42.51	silver quality
C1 segment of cervical spinal cord	UBERON:0006469	41.82	silver quality
subcutaneous adipose tissue	UBERON:0002190	41.81	silver quality
gastrocnemius	UBERON:0001388	41.75	silver quality
dorsolateral prefrontal cortex	UBERON:0009834	41.14	silver quality
caudate nucleus	UBERON:0001873	40.63	silver quality
hypothalamus	UBERON:0001898	40.55	gold quality
esophagus mucosa	UBERON:0002469	39.49	silver quality
body of stomach	UBERON:0001161	39.24	silver quality
upper lobe of left lung	UBERON:0008952	38.55	silver quality
anterior cingulate cortex	UBERON:0009835	38.03	silver quality
muscle layer of sigmoid colon	UBERON:0035805	37.00	silver quality
nucleus accumbens	UBERON:0001882	36.97	silver quality
omental fat pad	UBERON:0010414	36.44	silver quality
testis	UBERON:0000473	35.74	silver quality
left testis	UBERON:0004533	26.23	silver quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 1.

Experiment	Marker?	Max mean expression
E-ANND-3	yes	2.75

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.