LINC00375

Summary

LINC00375 (long intergenic non-protein coding RNA 375, HGNC:42699) is a long non-coding RNA gene on chromosome 13q31.1.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:42699
Approved symbol	LINC00375
Name	long intergenic non-protein coding RNA 375
Location	13q31.1
Locus type	RNA, long non-coding
Status	Approved
Ensembl gene	ENSG00000226370
Ensembl biotype	lncRNA
Entrez	104355140
RNAcentral	URS00007E394B — lncRNA, 631 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 14 — 14 lncRNA

ENST00000656022, ENST00000668831, ENST00000717724, ENST00000717725, ENST00000717726, ENST00000717727, ENST00000717728, ENST00000722540, ENST00000722541, ENST00000722542, ENST00000722543, ENST00000722544, ENST00000722545, ENST00000722546

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000656022 — 2 exons

Exon	Start	End
ENSE00003864792	85144623	85144874
ENSE00004033259	85148028	85148129

Expression profiles

Bgee: expression breadth broad, 44 present calls, max score 88.16.

Top tissues by expression

44 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
primordial germ cell in gonad	CL:0000670 ∩ UBERON:0000991	88.16	gold quality
male germ line stem cell (sensu Vertebrata) in testis	CL:0000089 ∩ UBERON:0000473	85.54	gold quality
monocyte	CL:0000576	58.90	gold quality
blood	UBERON:0000178	58.59	gold quality
calcaneal tendon	UBERON:0003701	54.33	gold quality
endometrium	UBERON:0001295	52.53	silver quality
right testis	UBERON:0004534	48.56	gold quality
testis	UBERON:0000473	48.06	gold quality
heart left ventricle	UBERON:0002084	47.77	gold quality
stomach	UBERON:0000945	47.45	gold quality
left testis	UBERON:0004533	46.16	gold quality
multicellular organism	UBERON:0000468	46.01	gold quality
esophagus	UBERON:0001043	45.34	gold quality
substantia nigra	UBERON:0002038	45.33	gold quality
left adrenal gland cortex	UBERON:0035825	44.89	gold quality
left adrenal gland	UBERON:0001234	44.63	gold quality
heart	UBERON:0000948	43.81	silver quality
adrenal tissue	UBERON:0018303	43.73	silver quality
esophagogastric junction muscularis propria	UBERON:0035841	43.68	silver quality
left lobe of thyroid gland	UBERON:0001120	42.72	silver quality
thyroid gland	UBERON:0002046	42.72	silver quality
gastrocnemius	UBERON:0001388	42.67	silver quality
body of uterus	UBERON:0009853	42.35	silver quality
tibial artery	UBERON:0007610	42.20	silver quality
smooth muscle tissue	UBERON:0001135	42.13	gold quality
skin of abdomen	UBERON:0001416	41.90	silver quality
prostate gland	UBERON:0002367	41.57	gold quality
ascending aorta	UBERON:0001496	41.56	silver quality
right atrium auricular region	UBERON:0006631	41.28	silver quality
left coronary artery	UBERON:0001626	41.14	silver quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 0.

Experiment	Marker?	Max mean expression
E-ANND-3	no	1.13

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.