LINC00377

Summary

LINC00377 (long intergenic non-protein coding RNA 377, HGNC:42703) is a long non-coding RNA gene on chromosome 13q31.1.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:42703
Approved symbol	LINC00377
Name	long intergenic non-protein coding RNA 377
Location	13q31.1
Locus type	RNA, long non-coding
Status	Approved
Aliases	TCONS_00021861
Ensembl gene	ENSG00000229246
Ensembl biotype	lncRNA
Entrez	103724386
RNAcentral	URS00007E3DA0 — lncRNA, 927 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 2 — 2 lncRNA

ENST00000456588, ENST00000663284

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000456588 — 2 exons

Exon	Start	End
ENSE00001665430	81043967	81044442
ENSE00001802647	81043670	81043850

Expression profiles

Bgee: expression breadth ubiquitous, 125 present calls, max score 85.07.

Top tissues by expression

125 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
sural nerve	UBERON:0015488	85.07	gold quality
male germ line stem cell (sensu Vertebrata) in testis	CL:0000089 ∩ UBERON:0000473	83.41	gold quality
primordial germ cell in gonad	CL:0000670 ∩ UBERON:0000991	83.35	gold quality
calcaneal tendon	UBERON:0003701	81.01	gold quality
tibial nerve	UBERON:0001323	78.23	gold quality
hindlimb stylopod muscle	UBERON:0004252	73.59	gold quality
skeletal muscle tissue	UBERON:0001134	72.99	gold quality
gastrocnemius	UBERON:0001388	72.32	gold quality
muscle of leg	UBERON:0001383	72.24	gold quality
colonic epithelium	UBERON:0000397	71.78	gold quality
subcutaneous adipose tissue	UBERON:0002190	66.14	gold quality
cerebellar cortex	UBERON:0002129	65.28	gold quality
cerebellar hemisphere	UBERON:0002245	65.25	gold quality
cerebellum	UBERON:0002037	65.23	gold quality
adipose tissue	UBERON:0001013	64.81	gold quality
thoracic mammary gland	UBERON:0005200	64.00	gold quality
right hemisphere of cerebellum	UBERON:0014890	63.82	gold quality
tonsil	UBERON:0002372	63.48	silver quality
omental fat pad	UBERON:0010414	63.22	gold quality
lower esophagus muscularis layer	UBERON:0035833	63.19	gold quality
lower esophagus	UBERON:0013473	63.16	gold quality
muscle layer of sigmoid colon	UBERON:0035805	61.63	gold quality
ventricular zone	UBERON:0003053	60.74	gold quality
heart left ventricle	UBERON:0002084	59.93	gold quality
esophagogastric junction muscularis propria	UBERON:0035841	59.74	gold quality
apex of heart	UBERON:0002098	59.60	gold quality
ganglionic eminence	UBERON:0004023	59.19	gold quality
right lung	UBERON:0002167	59.02	gold quality
popliteal artery	UBERON:0002250	58.15	gold quality
tibial artery	UBERON:0007610	58.11	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 1.

Experiment	Marker?	Max mean expression
E-ANND-3	yes	6.68

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.