LINC00402

Summary

LINC00402 (long intergenic non-protein coding RNA 402, HGNC:42732) is a long non-coding RNA gene on chromosome 13q22.1.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:42732
Approved symbol	LINC00402
Name	long intergenic non-protein coding RNA 402
Location	13q22.1
Locus type	RNA, long non-coding
Status	Approved
Ensembl gene	ENSG00000235532
Ensembl biotype	lncRNA
Entrez	100507612
RNAcentral	URS0000A76535 — lncRNA, 3353 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 16 — 16 lncRNA

ENST00000419499, ENST00000423629, ENST00000649990, ENST00000653841, ENST00000653992, ENST00000654479, ENST00000655413, ENST00000658820, ENST00000662433, ENST00000662799, ENST00000663108, ENST00000664361, ENST00000664844, ENST00000669178, ENST00000715466, ENST00000715848

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000419499 — 2 exons

Exon	Start	End
ENSE00001708221	74231401	74231752
ENSE00001723854	74256933	74259976

Expression profiles

Bgee: expression breadth broad, 74 present calls, max score 77.44.

FANTOM5 (CAGE): breadth tissue_specific, TPM avg 2.2373 / max 440.3558, expressed in 68 samples.

FANTOM5 promoters (2 alternative TSS)

Promoter ID	TPM avg	Samples expressed
135388	1.9937	68
135389	0.2436	44

Top tissues by expression

74 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
male germ line stem cell (sensu Vertebrata) in testis	CL:0000089 ∩ UBERON:0000473	77.44	silver quality
testis	UBERON:0000473	75.23	silver quality
lymph node	UBERON:0000029	73.62	gold quality
bone marrow cell	CL:0002092	69.42	silver quality
adrenal gland	UBERON:0002369	67.91	gold quality
tonsil	UBERON:0002372	67.75	gold quality
vermiform appendix	UBERON:0001154	67.36	gold quality
leukocyte	CL:0000738	66.01	gold quality
granulocyte	CL:0000094	63.20	gold quality
blood	UBERON:0000178	62.53	gold quality
liver	UBERON:0002107	58.12	gold quality
bone marrow	UBERON:0002371	55.83	gold quality
right lobe of liver	UBERON:0001114	55.62	gold quality
anterior cingulate cortex	UBERON:0009835	55.53	gold quality
spleen	UBERON:0002106	55.00	gold quality
primordial germ cell in gonad	CL:0000670 ∩ UBERON:0000991	54.71	gold quality
small intestine	UBERON:0002108	54.45	gold quality
small intestine Peyer’s patch	UBERON:0003454	54.33	gold quality
multicellular organism	UBERON:0000468	54.26	gold quality
duodenum	UBERON:0002114	53.24	gold quality
rectum	UBERON:0001052	52.38	gold quality
urinary bladder	UBERON:0001255	51.43	gold quality
muscle of leg	UBERON:0001383	51.42	gold quality
intestine	UBERON:0000160	50.14	gold quality
primary visual cortex	UBERON:0002436	48.47	silver quality
monocyte	CL:0000576	48.44	silver quality
islet of Langerhans	UBERON:0000006	48.08	silver quality
gastrocnemius	UBERON:0001388	47.59	gold quality
gall bladder	UBERON:0002110	47.53	gold quality
brain	UBERON:0000955	47.04	silver quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 1.

Experiment	Marker?	Max mean expression
E-ANND-3	yes	5.00

Regulation

Is transcription factor: no

Literature-anchored findings (GeneRIF, showing 1)

• RNA-seq of human T cells after hematopoietic stem cell transplantation identifies Linc00402 as a regulator of T cell alloimmunity. (PMID:33731431)

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.