LINC00408

Summary

LINC00408 (long intergenic non-protein coding RNA 408, HGNC:42740) is a long non-coding RNA gene on chromosome 13q12.11.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:42740
Approved symbol	LINC00408
Name	long intergenic non-protein coding RNA 408
Location	13q12.11
Locus type	RNA, long non-coding
Status	Approved
Ensembl gene	ENSG00000226250
Ensembl biotype	lncRNA
Entrez	100652856
RNAcentral	URS000075BD4F — lncRNA, 1081 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 13 — 13 lncRNA

ENST00000447784, ENST00000653982, ENST00000660513, ENST00000663325, ENST00000663501, ENST00000663692, ENST00000664751, ENST00000665951, ENST00000668892, ENST00000669381, ENST00000671023, ENST00000761568, ENST00000761569

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000447784 — 4 exons

Exon	Start	End
ENSE00001621790	18906027	18906110
ENSE00001650686	18907635	18907810
ENSE00001665780	18906497	18906658
ENSE00001780659	18905439	18905576

Expression profiles

Bgee: expression breadth broad, 58 present calls, max score 95.34.

Top tissues by expression

170 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
buccal mucosa cell	CL:0002336	95.34	gold quality
male germ line stem cell (sensu Vertebrata) in testis	CL:0000089 ∩ UBERON:0000473	82.77	gold quality
left testis	UBERON:0004533	77.58	gold quality
testis	UBERON:0000473	76.66	gold quality
right testis	UBERON:0004534	76.25	gold quality
sperm	CL:0000019	67.66	gold quality
adult organism	UBERON:0007023	60.14	gold quality
myocardium	UBERON:0002349	58.93	gold quality
C1 segment of cervical spinal cord	UBERON:0006469	58.89	gold quality
primordial germ cell in gonad	CL:0000670 ∩ UBERON:0000991	55.26	gold quality
lower lobe of lung	UBERON:0008949	55.13	silver quality
monocyte	CL:0000576	54.64	gold quality
medial globus pallidus	UBERON:0002477	54.46	silver quality
endothelial cell	CL:0000115	54.26	gold quality
gastrocnemius	UBERON:0001388	50.29	gold quality
body of pancreas	UBERON:0001150	49.04	gold quality
upper lobe of lung	UBERON:0008948	48.54	silver quality
middle temporal gyrus	UBERON:0002771	48.41	gold quality
pancreas	UBERON:0001264	47.70	gold quality
tibial nerve	UBERON:0001323	46.90	gold quality
anatomical system	UBERON:0000467	46.09	gold quality
material anatomical entity	UBERON:0000465	45.76	gold quality
multicellular organism	UBERON:0000468	45.71	gold quality
cerebellar hemisphere	UBERON:0002245	45.71	silver quality
heart right ventricle	UBERON:0002080	45.70	gold quality
islet of Langerhans	UBERON:0000006	45.67	gold quality
lateral nuclear group of thalamus	UBERON:0002736	45.54	gold quality
substantia nigra pars reticulata	UBERON:0001966	45.51	gold quality
lung	UBERON:0002048	45.40	silver quality
trabecular bone tissue	UBERON:0002483	45.36	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 0.

Experiment	Marker?	Max mean expression
E-ANND-3	no	0.16

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.