LINC00421

Summary

LINC00421 (long intergenic non-protein coding RNA 421, HGNC:42755) is a long non-coding RNA gene on chromosome 13q12.11.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:42755
Approved symbol	LINC00421
Name	long intergenic non-protein coding RNA 421
Location	13q12.11
Locus type	RNA, long non-coding
Status	Approved
Ensembl gene	ENSG00000236834
Ensembl biotype	lncRNA
Entrez	100287114
RNAcentral	URS000075D17E — lncRNA, 1067 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 4 — 4 lncRNA

ENST00000413833, ENST00000827421, ENST00000827422, ENST00000827423

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000413833 — 2 exons

Exon	Start	End
ENSE00004239284	19344573	19345217
ENSE00004239285	19345865	19346810

Expression profiles

Bgee: expression breadth broad, 38 present calls, max score 59.23.

Top tissues by expression

164 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
right testis	UBERON:0004534	59.23	gold quality
parotid gland	UBERON:0001831	58.57	gold quality
skeletal muscle tissue of rectus abdominis	UBERON:0004511	58.49	gold quality
left testis	UBERON:0004533	57.42	gold quality
testis	UBERON:0000473	56.94	gold quality
saliva-secreting gland	UBERON:0001044	53.28	gold quality
endothelial cell	CL:0000115	52.14	gold quality
buccal mucosa cell	CL:0002336	51.97	gold quality
cerebellar vermis	UBERON:0004720	51.66	gold quality
upper leg skin	UBERON:0004262	51.25	silver quality
sperm	CL:0000019	50.77	gold quality
Brodmann (1909) area 46	UBERON:0006483	50.59	gold quality
monocyte	CL:0000576	50.42	silver quality
nasal cavity epithelium	UBERON:0005384	50.41	gold quality
primordial germ cell in gonad	CL:0000670 ∩ UBERON:0000991	49.97	silver quality
biceps brachii	UBERON:0001507	48.98	gold quality
gastrocnemius	UBERON:0001388	47.90	gold quality
deltoid	UBERON:0001476	46.61	gold quality
prefrontal cortex	UBERON:0000451	46.53	silver quality
vermiform appendix	UBERON:0001154	46.34	silver quality
dorsolateral prefrontal cortex	UBERON:0009834	46.09	silver quality
skin of hip	UBERON:0001554	46.06	silver quality
skeletal muscle tissue	UBERON:0001134	45.76	gold quality
left adrenal gland cortex	UBERON:0035825	45.53	gold quality
mouth mucosa	UBERON:0003729	44.51	gold quality
tibial artery	UBERON:0007610	44.20	gold quality
gall bladder	UBERON:0002110	44.10	silver quality
right lobe of liver	UBERON:0001114	43.95	silver quality
gingiva	UBERON:0001828	43.90	gold quality
C1 segment of cervical spinal cord	UBERON:0006469	43.73	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 0.

Experiment	Marker?	Max mean expression
E-ANND-3	no	0.32

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.