LINC00433

Summary

LINC00433 (long intergenic non-protein coding RNA 433, HGNC:42768) is a long non-coding RNA gene on chromosome 13q31.2.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:42768
Approved symbol	LINC00433
Name	long intergenic non-protein coding RNA 433
Location	13q31.2
Locus type	RNA, long non-coding
Status	Approved
Ensembl gene	ENSG00000229443
Ensembl biotype	lncRNA
Entrez	100874168
RNAcentral	URS000075D6DE — lncRNA, 853 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 6 — 6 lncRNA

ENST00000424165, ENST00000448425, ENST00000564593, ENST00000653293, ENST00000658219, ENST00000715718

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000424165 — 3 exons

Exon	Start	End
ENSE00001706897	88540864	88541443
ENSE00001778011	88542270	88542506
ENSE00001800183	88541902	88541972

Expression profiles

Bgee: expression breadth broad, 51 present calls, max score 86.98.

Top tissues by expression

51 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
male germ line stem cell (sensu Vertebrata) in testis	CL:0000089 ∩ UBERON:0000473	86.98	gold quality
sural nerve	UBERON:0015488	69.83	gold quality
liver	UBERON:0002107	63.68	silver quality
primordial germ cell in gonad	CL:0000670 ∩ UBERON:0000991	60.07	gold quality
muscle tissue	UBERON:0002385	59.92	silver quality
monocyte	CL:0000576	57.22	gold quality
hindlimb stylopod muscle	UBERON:0004252	54.39	silver quality
blood	UBERON:0000178	54.36	gold quality
kidney	UBERON:0002113	53.63	silver quality
testis	UBERON:0000473	51.27	gold quality
gall bladder	UBERON:0002110	51.18	gold quality
left testis	UBERON:0004533	51.07	gold quality
right testis	UBERON:0004534	50.34	gold quality
multicellular organism	UBERON:0000468	49.38	gold quality
lung	UBERON:0002048	47.63	gold quality
islet of Langerhans	UBERON:0000006	47.59	gold quality
right frontal lobe	UBERON:0002810	46.10	gold quality
muscle of leg	UBERON:0001383	45.84	silver quality
brain	UBERON:0000955	45.80	gold quality
tibial nerve	UBERON:0001323	45.47	silver quality
hypothalamus	UBERON:0001898	45.26	gold quality
gastrocnemius	UBERON:0001388	44.63	silver quality
muscle layer of sigmoid colon	UBERON:0035805	44.09	gold quality
tibial artery	UBERON:0007610	44.01	silver quality
esophagus mucosa	UBERON:0002469	43.88	silver quality
Ammon’s horn	UBERON:0001954	43.83	silver quality
lower esophagus mucosa	UBERON:0035834	43.22	silver quality
placenta	UBERON:0001987	42.68	silver quality
heart left ventricle	UBERON:0002084	42.53	silver quality
left ovary	UBERON:0002119	42.32	silver quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 0.

Experiment	Marker?	Max mean expression
E-ANND-3	no	2.45

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.