LINC00434

Summary

LINC00434 (long intergenic non-protein coding RNA 434, HGNC:42769) is a long non-coding RNA gene on chromosome 13q21.2.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:42769
Approved symbol	LINC00434
Name	long intergenic non-protein coding RNA 434
Location	13q21.2
Locus type	RNA, long non-coding
Status	Approved
Ensembl gene	ENSG00000227336
Ensembl biotype	lncRNA
Entrez	100874169
RNAcentral	URS000081220A — lncRNA, 972 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 7 — 7 lncRNA

ENST00000423739, ENST00000755621, ENST00000755622, ENST00000755623, ENST00000755624, ENST00000755625, ENST00000755626

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000423739 — 2 exons

Exon	Start	End
ENSE00001678846	60214352	60214701
ENSE00001734947	60214878	60214946

Expression profiles

Bgee: expression breadth broad, 68 present calls, max score 63.01.

Top tissues by expression

68 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
prefrontal cortex	UBERON:0000451	63.01	gold quality
islet of Langerhans	UBERON:0000006	58.76	gold quality
left coronary artery	UBERON:0001626	56.28	gold quality
pancreas	UBERON:0001264	56.11	gold quality
body of pancreas	UBERON:0001150	55.63	gold quality
cortex of kidney	UBERON:0001225	55.51	gold quality
blood	UBERON:0000178	54.89	gold quality
monocyte	CL:0000576	52.84	silver quality
fundus of stomach	UBERON:0001160	50.57	gold quality
heart left ventricle	UBERON:0002084	50.27	gold quality
esophagogastric junction muscularis propria	UBERON:0035841	49.30	gold quality
heart	UBERON:0000948	48.77	gold quality
urinary bladder	UBERON:0001255	48.62	gold quality
popliteal artery	UBERON:0002250	48.38	gold quality
body of stomach	UBERON:0001161	48.37	gold quality
tibial artery	UBERON:0007610	48.33	gold quality
stomach	UBERON:0000945	48.24	gold quality
right adrenal gland cortex	UBERON:0035827	47.97	gold quality
omental fat pad	UBERON:0010414	47.42	gold quality
lower esophagus muscularis layer	UBERON:0035833	47.11	gold quality
kidney	UBERON:0002113	47.04	gold quality
subcutaneous adipose tissue	UBERON:0002190	46.97	gold quality
right coronary artery	UBERON:0001625	46.85	gold quality
cerebellar hemisphere	UBERON:0002245	46.70	silver quality
ascending aorta	UBERON:0001496	46.57	gold quality
lung	UBERON:0002048	46.34	gold quality
substantia nigra	UBERON:0002038	46.01	gold quality
mucosa of transverse colon	UBERON:0004991	45.78	gold quality
adult mammalian kidney	UBERON:0000082	45.69	gold quality
esophagus mucosa	UBERON:0002469	45.66	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 0.

Experiment	Marker?	Max mean expression
E-ANND-3	no	0.80

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.