LINC00437

Summary

LINC00437 (long intergenic non-protein coding RNA 437, HGNC:42772) is a long non-coding RNA gene on chromosome 13q13.3.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:42772
Approved symbol	LINC00437
Name	long intergenic non-protein coding RNA 437
Location	13q13.3
Locus type	RNA, long non-coding
Status	Approved
Aliases	TCONS_00021639
Ensembl gene	ENSG00000236354
Ensembl biotype	lncRNA
Entrez	101929121
RNAcentral	URS00007E4311 — lncRNA, 2359 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 15 — 15 lncRNA

ENST00000414161, ENST00000756067, ENST00000756068, ENST00000756069, ENST00000756070, ENST00000756071, ENST00000756072, ENST00000756073, ENST00000756074, ENST00000756075, ENST00000756076, ENST00000756077, ENST00000756078, ENST00000756079, ENST00000756080

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000414161 — 2 exons

Exon	Start	End
ENSE00001613832	38545187	38545299
ENSE00001723883	38533343	38534020

Expression profiles

Bgee: expression breadth broad, 55 present calls, max score 90.33.

Top tissues by expression

176 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
primordial germ cell in gonad	CL:0000670 ∩ UBERON:0000991	90.33	gold quality
hindlimb stylopod muscle	UBERON:0004252	65.72	gold quality
ventricular zone	UBERON:0003053	63.39	gold quality
monocyte	CL:0000576	62.07	gold quality
buccal mucosa cell	CL:0002336	54.37	silver quality
prefrontal cortex	UBERON:0000451	53.52	gold quality
islet of Langerhans	UBERON:0000006	51.87	gold quality
lower lobe of lung	UBERON:0008949	51.10	silver quality
muscle of leg	UBERON:0001383	50.24	gold quality
caudate nucleus	UBERON:0001873	49.14	gold quality
anterior cingulate cortex	UBERON:0009835	48.71	gold quality
amygdala	UBERON:0001876	47.58	gold quality
nucleus accumbens	UBERON:0001882	47.58	gold quality
neocortex	UBERON:0001950	47.15	gold quality
right hemisphere of cerebellum	UBERON:0014890	46.97	gold quality
frontal cortex	UBERON:0001870	46.93	gold quality
right frontal lobe	UBERON:0002810	46.71	gold quality
Brodmann (1909) area 9	UBERON:0013540	46.68	gold quality
gastrocnemius	UBERON:0001388	46.34	gold quality
putamen	UBERON:0001874	46.17	gold quality
dorsolateral prefrontal cortex	UBERON:0009834	46.17	gold quality
cerebellar hemisphere	UBERON:0002245	45.90	gold quality
gall bladder	UBERON:0002110	45.80	gold quality
forebrain	UBERON:0001890	45.40	gold quality
cerebral cortex	UBERON:0000956	45.21	gold quality
brain	UBERON:0000955	45.06	gold quality
transverse colon	UBERON:0001157	43.51	gold quality
skeletal muscle tissue of rectus abdominis	UBERON:0004511	43.37	gold quality
primary visual cortex	UBERON:0002436	43.24	gold quality
cerebellum	UBERON:0002037	43.18	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 0.

Experiment	Marker?	Max mean expression
E-ANND-3	no	1.99

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.