LINC00440

Summary

LINC00440 (long intergenic non-protein coding RNA 440, HGNC:42777) is a long non-coding RNA gene on chromosome 13q31.2.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:42777
Approved symbol	LINC00440
Name	long intergenic non-protein coding RNA 440
Location	13q31.2
Locus type	RNA, long non-coding
Status	Approved
Ensembl gene	ENSG00000234660
Ensembl biotype	lncRNA
Entrez	100874172
RNAcentral	URS00008121DE — lncRNA, 868 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 2 — 2 lncRNA

ENST00000446579, ENST00000653072

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000446579 — 2 exons

Exon	Start	End
ENSE00001628684	89273203	89273362
ENSE00001784593	89279667	89280240

Expression profiles

Bgee: expression breadth ubiquitous, 109 present calls, max score 91.91.

Top tissues by expression

109 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
primordial germ cell in gonad	CL:0000670 ∩ UBERON:0000991	91.91	gold quality
male germ line stem cell (sensu Vertebrata) in testis	CL:0000089 ∩ UBERON:0000473	80.75	silver quality
ventricular zone	UBERON:0003053	63.86	gold quality
colonic epithelium	UBERON:0000397	63.53	silver quality
ganglionic eminence	UBERON:0004023	62.54	gold quality
cortical plate	UBERON:0005343	61.35	gold quality
monocyte	CL:0000576	58.98	gold quality
hindlimb stylopod muscle	UBERON:0004252	58.71	gold quality
liver	UBERON:0002107	58.06	gold quality
prefrontal cortex	UBERON:0000451	57.71	gold quality
right lobe of liver	UBERON:0001114	57.69	gold quality
skeletal muscle tissue	UBERON:0001134	56.30	gold quality
calcaneal tendon	UBERON:0003701	56.13	silver quality
dorsolateral prefrontal cortex	UBERON:0009834	55.61	gold quality
superior frontal gyrus	UBERON:0002661	55.24	gold quality
Brodmann (1909) area 9	UBERON:0013540	55.00	gold quality
frontal cortex	UBERON:0001870	54.13	gold quality
cerebral cortex	UBERON:0000956	53.58	gold quality
anterior cingulate cortex	UBERON:0009835	52.98	gold quality
stromal cell of endometrium	CL:0002255	52.55	silver quality
duodenum	UBERON:0002114	52.29	gold quality
corpus callosum	UBERON:0002336	51.45	silver quality
islet of Langerhans	UBERON:0000006	51.20	gold quality
sural nerve	UBERON:0015488	51.02	silver quality
blood	UBERON:0000178	50.86	silver quality
brain	UBERON:0000955	50.42	gold quality
right frontal lobe	UBERON:0002810	49.30	gold quality
lymph node	UBERON:0000029	48.86	gold quality
primary visual cortex	UBERON:0002436	48.22	silver quality
temporal lobe	UBERON:0001871	48.11	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 0.

Experiment	Marker?	Max mean expression
E-ANND-3	no	1.47

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.