LINC00445

Summary

LINC00445 (long intergenic non-protein coding RNA 445, HGNC:42782) is a long non-coding RNA gene on chromosome 13q13.3.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:42782
Approved symbol	LINC00445
Name	long intergenic non-protein coding RNA 445
Location	13q13.3
Locus type	RNA, long non-coding
Status	Approved
Ensembl gene	ENSG00000236036
Ensembl biotype	lncRNA
Entrez	100507114
RNAcentral	URS00002F8A2B — lncRNA, 643 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 6 — 6 lncRNA

ENST00000422430, ENST00000456848, ENST00000655817, ENST00000656633, ENST00000670790, ENST00000835900

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000422430 — 2 exons

Exon	Start	End
ENSE00001649833	35697524	35697636
ENSE00001700526	35698739	35699001

Expression profiles

Bgee: expression breadth broad, 62 present calls, max score 87.20.

Top tissues by expression

187 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
pancreatic ductal cell	CL:0002079	87.20	silver quality
left testis	UBERON:0004533	72.71	gold quality
right testis	UBERON:0004534	71.83	gold quality
primordial germ cell in gonad	CL:0000670 ∩ UBERON:0000991	69.92	gold quality
testis	UBERON:0000473	69.69	gold quality
sperm	CL:0000019	68.16	silver quality
ileal mucosa	UBERON:0000331	63.53	silver quality
tibialis anterior	UBERON:0001385	62.16	silver quality
buccal mucosa cell	CL:0002336	61.15	silver quality
monocyte	CL:0000576	56.60	gold quality
hindlimb stylopod muscle	UBERON:0004252	55.73	silver quality
deltoid	UBERON:0001476	55.63	gold quality
cardiac muscle of right atrium	UBERON:0003379	54.34	gold quality
left ventricle myocardium	UBERON:0006566	54.23	gold quality
prefrontal cortex	UBERON:0000451	54.04	gold quality
right lobe of liver	UBERON:0001114	53.94	gold quality
kidney epithelium	UBERON:0004819	53.93	gold quality
upper arm skin	UBERON:0004263	53.52	gold quality
muscle of leg	UBERON:0001383	53.34	gold quality
cartilage tissue	UBERON:0002418	52.63	gold quality
gastrocnemius	UBERON:0001388	51.92	gold quality
cerebellar vermis	UBERON:0004720	51.57	gold quality
myocardium	UBERON:0002349	50.25	gold quality
body of stomach	UBERON:0001161	49.63	gold quality
quadriceps femoris	UBERON:0001377	49.28	gold quality
nasal cavity epithelium	UBERON:0005384	47.03	gold quality
vastus lateralis	UBERON:0001379	46.93	gold quality
layer of synovial tissue	UBERON:0007616	46.53	gold quality
skeletal muscle tissue	UBERON:0001134	46.38	gold quality
anterior cingulate cortex	UBERON:0009835	46.28	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 0.

Experiment	Marker?	Max mean expression
E-ANND-3	no	1.47

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.