LINC00456

Summary

LINC00456 (long intergenic non-protein coding RNA 456, HGNC:42804) is a long non-coding RNA gene on chromosome 13q32.1.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:42804
Approved symbol	LINC00456
Name	long intergenic non-protein coding RNA 456
Location	13q32.1
Locus type	RNA, long non-coding
Status	Approved
Ensembl gene	ENSG00000233124
Ensembl biotype	lncRNA
Entrez	103625683
RNAcentral	URS00007E3441 — lncRNA, 779 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 10 — 10 lncRNA

ENST00000453862, ENST00000657031, ENST00000820900, ENST00000820901, ENST00000820902, ENST00000820903, ENST00000820904, ENST00000820905, ENST00000820906, ENST00000820907

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000453862 — 2 exons

Exon	Start	End
ENSE00004227275	97179327	97179666
ENSE00004227284	97171529	97172864

Expression profiles

Bgee: expression breadth broad, 59 present calls, max score 79.21.

FANTOM5 (CAGE): breadth tissue_specific, TPM avg 0.0744 / max 58.2453, expressed in 11 samples.

FANTOM5 promoters (2 alternative TSS)

Promoter ID	TPM avg	Samples expressed
137903	0.0617	10
207078	0.0127	6

Top tissues by expression

65 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
skeletal muscle tissue	UBERON:0001134	79.21	silver quality
spleen	UBERON:0002106	77.46	silver quality
pancreas	UBERON:0001264	77.26	silver quality
thymus	UBERON:0002370	76.55	silver quality
placenta	UBERON:0001987	73.47	gold quality
bone marrow cell	CL:0002092	65.76	silver quality
quadriceps femoris	UBERON:0001377	64.14	gold quality
colonic epithelium	UBERON:0000397	63.22	silver quality
cerebellar vermis	UBERON:0004720	63.05	gold quality
liver	UBERON:0002107	62.45	gold quality
heart	UBERON:0000948	61.39	silver quality
adrenal gland	UBERON:0002369	58.91	silver quality
right atrium auricular region	UBERON:0006631	58.53	gold quality
prefrontal cortex	UBERON:0000451	50.94	gold quality
olfactory segment of nasal mucosa	UBERON:0005386	50.24	gold quality
monocyte	CL:0000576	49.31	silver quality
right uterine tube	UBERON:0001302	48.85	gold quality
gastrocnemius	UBERON:0001388	48.21	silver quality
urinary bladder	UBERON:0001255	47.40	gold quality
colon	UBERON:0001155	46.91	gold quality
adrenal tissue	UBERON:0018303	46.57	silver quality
frontal cortex	UBERON:0001870	46.34	gold quality
superior frontal gyrus	UBERON:0002661	46.32	silver quality
blood	UBERON:0000178	46.03	silver quality
stomach	UBERON:0000945	46.00	gold quality
intestine	UBERON:0000160	45.93	gold quality
right lobe of liver	UBERON:0001114	44.93	silver quality
vagina	UBERON:0000996	44.92	gold quality
multicellular organism	UBERON:0000468	44.68	gold quality
ovary	UBERON:0000992	44.17	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 0.

Experiment	Marker?	Max mean expression
E-ANND-3	no	1.13

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.