LINC00459

Summary

LINC00459 (long intergenic non-protein coding RNA 459, HGNC:42808) is a long non-coding RNA gene on chromosome 13q21.31.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:42808
Approved symbol	LINC00459
Name	long intergenic non-protein coding RNA 459
Location	13q21.31
Locus type	RNA, long non-coding
Status	Approved
Ensembl gene	ENSG00000229307
Ensembl biotype	lncRNA
Entrez	100874180
RNAcentral	URS0000BC454A — lncRNA, 390 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 1 — 1 lncRNA

ENST00000431656

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000431656 — 2 exons

Exon	Start	End
ENSE00001697068	62328756	62328833
ENSE00001767734	62323657	62323954

Expression profiles

Bgee: expression breadth broad, 35 present calls, max score 89.67.

Top tissues by expression

179 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
buccal mucosa cell	CL:0002336	89.67	gold quality
male germ line stem cell (sensu Vertebrata) in testis	CL:0000089 ∩ UBERON:0000473	89.57	gold quality
ileal mucosa	UBERON:0000331	64.87	gold quality
pancreatic ductal cell	CL:0002079	63.09	silver quality
tibialis anterior	UBERON:0001385	60.87	silver quality
gastrocnemius	UBERON:0001388	58.39	gold quality
epithelial cell of pancreas	CL:0000083	55.03	gold quality
islet of Langerhans	UBERON:0000006	54.79	gold quality
cardiac muscle of right atrium	UBERON:0003379	54.34	gold quality
left ventricle myocardium	UBERON:0006566	54.23	gold quality
kidney epithelium	UBERON:0004819	53.93	gold quality
upper arm skin	UBERON:0004263	53.52	gold quality
Brodmann (1909) area 9	UBERON:0013540	51.82	gold quality
deltoid	UBERON:0001476	50.99	gold quality
myocardium	UBERON:0002349	50.25	gold quality
C1 segment of cervical spinal cord	UBERON:0006469	49.48	gold quality
muscle tissue	UBERON:0002385	47.98	gold quality
ovary	UBERON:0000992	47.76	silver quality
anterior cingulate cortex	UBERON:0009835	47.53	gold quality
quadriceps femoris	UBERON:0001377	47.04	gold quality
spinal cord	UBERON:0002240	47.04	gold quality
nasal cavity epithelium	UBERON:0005384	47.03	gold quality
adrenal tissue	UBERON:0018303	47.02	silver quality
body of pancreas	UBERON:0001150	46.71	silver quality
metanephros	UBERON:0000081	46.07	gold quality
vastus lateralis	UBERON:0001379	45.40	gold quality
skeletal muscle tissue	UBERON:0001134	45.11	gold quality
right atrium auricular region	UBERON:0006631	45.03	gold quality
adult mammalian kidney	UBERON:0000082	44.98	gold quality
heart left ventricle	UBERON:0002084	43.84	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 0.

Experiment	Marker?	Max mean expression
E-ANND-3	no	1.14

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.