LINC00462

Summary

LINC00462 (long intergenic non-protein coding RNA 462, HGNC:42811) is a long non-coding RNA gene on chromosome 13q14.2.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:42811
Approved symbol	LINC00462
Name	long intergenic non-protein coding RNA 462
Location	13q14.2
Locus type	RNA, long non-coding
Status	Approved
Ensembl gene	ENSG00000233610
Ensembl biotype	lncRNA
Entrez	100129597
RNAcentral	URS000075E928 — lncRNA, 1023 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 7 — 7 lncRNA

ENST00000425350, ENST00000689307, ENST00000689759, ENST00000810565, ENST00000810566, ENST00000810567, ENST00000810568

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000425350 — 3 exons

Exon	Start	End
ENSE00001644593	48578013	48578088
ENSE00004207582	48576970	48577859
ENSE00004207585	48590486	48590598

Expression profiles

Bgee: expression breadth broad, 84 present calls, max score 74.14.

FANTOM5 (CAGE): breadth tissue_specific, TPM avg 0.0710 / max 32.0188, expressed in 14 samples.

FANTOM5 promoters (1 alternative TSS)

Promoter ID	TPM avg	Samples expressed
137289	0.0710	14

Top tissues by expression

191 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
sural nerve	UBERON:0015488	74.14	gold quality
tibial nerve	UBERON:0001323	63.68	gold quality
skin of leg	UBERON:0001511	58.14	gold quality
cortex of kidney	UBERON:0001225	58.05	gold quality
upper leg skin	UBERON:0004262	57.17	silver quality
primordial germ cell in gonad	CL:0000670 ∩ UBERON:0000991	56.01	gold quality
zone of skin	UBERON:0000014	54.94	gold quality
skin of abdomen	UBERON:0001416	54.50	gold quality
muscle layer of sigmoid colon	UBERON:0035805	53.19	gold quality
vermiform appendix	UBERON:0001154	52.93	gold quality
islet of Langerhans	UBERON:0000006	52.38	gold quality
lower esophagus muscularis layer	UBERON:0035833	51.94	gold quality
lower esophagus	UBERON:0013473	51.93	gold quality
esophagus	UBERON:0001043	50.73	gold quality
esophagogastric junction muscularis propria	UBERON:0035841	49.89	gold quality
esophagus mucosa	UBERON:0002469	49.70	gold quality
monocyte	CL:0000576	49.54	silver quality
pancreas	UBERON:0001264	48.78	gold quality
skin of hip	UBERON:0001554	48.75	silver quality
muscle of leg	UBERON:0001383	48.48	silver quality
colon	UBERON:0001155	48.09	gold quality
dorsal root ganglion	UBERON:0000044	48.04	silver quality
body of stomach	UBERON:0001161	47.79	gold quality
large intestine	UBERON:0000059	47.63	gold quality
intestine	UBERON:0000160	47.34	gold quality
anatomical system	UBERON:0000467	47.16	gold quality
left coronary artery	UBERON:0001626	47.03	gold quality
gastrocnemius	UBERON:0001388	47.02	silver quality
anterior cingulate cortex	UBERON:0009835	46.97	gold quality
multicellular organism	UBERON:0000468	46.88	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 0.

Experiment	Marker?	Max mean expression
E-ANND-3	no	0.82

Regulation

Is transcription factor: no

Literature-anchored findings (GeneRIF, showing 1)

• A comprehensive review of the role of LINC00462 in human disorders. (PMID:36812739)

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.