LINC00477

Summary

LINC00477 (long intergenic non-protein coding RNA 477, HGNC:26557) is a long non-coding RNA gene on chromosome 12p12.1.

Predicted to be located in membrane.

Source: NCBI Gene 144360 — RefSeq curated summary.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:26557
Approved symbol	LINC00477
Name	long intergenic non-protein coding RNA 477
Location	12p12.1
Locus type	RNA, long non-coding
Status	Approved
Aliases	FLJ32894, FAM191B
Ensembl gene	ENSG00000197503
Ensembl biotype	lncRNA
Entrez	144360
RNAcentral	URS00006158E3 — lncRNA, 1710 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 3 — 3 lncRNA

ENST00000483544, ENST00000764662, ENST00000764663

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000483544 — 4 exons

Exon	Start	End
ENSE00001523549	24566964	24567208
ENSE00001523553	24567662	24567789
ENSE00001523555	24571534	24571657
ENSE00001939569	24582956	24584168

Expression profiles

Bgee: expression breadth broad, 36 present calls, max score 82.29.

FANTOM5 (CAGE): breadth tissue_specific, TPM avg 0.1170 / max 34.9901, expressed in 24 samples.

FANTOM5 promoters (1 alternative TSS)

Promoter ID	TPM avg	Samples expressed
130111	0.1170	24

Top tissues by expression

166 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
buccal mucosa cell	CL:0002336	82.29	silver quality
ganglionic eminence	UBERON:0004023	59.89	gold quality
left testis	UBERON:0004533	58.86	gold quality
right testis	UBERON:0004534	58.82	gold quality
testis	UBERON:0000473	57.00	gold quality
islet of Langerhans	UBERON:0000006	48.46	silver quality
monocyte	CL:0000576	48.40	silver quality
smooth muscle tissue	UBERON:0001135	45.43	silver quality
prefrontal cortex	UBERON:0000451	45.21	silver quality
gastrocnemius	UBERON:0001388	44.92	silver quality
skeletal muscle tissue of rectus abdominis	UBERON:0004511	43.37	gold quality
secondary oocyte	CL:0000655	42.57	gold quality
transverse colon	UBERON:0001157	42.53	gold quality
anatomical system	UBERON:0000467	42.46	gold quality
multicellular organism	UBERON:0000468	42.34	gold quality
blood	UBERON:0000178	42.33	silver quality
material anatomical entity	UBERON:0000465	42.33	gold quality
left adrenal gland cortex	UBERON:0035825	42.32	silver quality
right adrenal gland cortex	UBERON:0035827	42.08	silver quality
lower lobe of lung	UBERON:0008949	41.73	silver quality
spleen	UBERON:0002106	41.58	silver quality
vastus lateralis	UBERON:0001379	41.41	gold quality
quadriceps femoris	UBERON:0001377	41.37	gold quality
C1 segment of cervical spinal cord	UBERON:0006469	41.37	silver quality
adult mammalian kidney	UBERON:0000082	41.34	gold quality
superficial temporal artery	UBERON:0001614	41.33	gold quality
vagina	UBERON:0000996	41.30	gold quality
bone marrow	UBERON:0002371	41.14	gold quality
skeletal muscle tissue	UBERON:0001134	41.10	gold quality
palpebral conjunctiva	UBERON:0001812	41.10	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 0.

Experiment	Marker?	Max mean expression
E-ANND-3	no	2.30

Regulation

Is transcription factor: no

Literature-anchored findings (GeneRIF, showing 1)

• The LINC00477/miR-128 axis promotes the progression of polycystic ovary syndrome by regulating ovarian granulosa cell proliferation and apoptosis. (PMID:33622342)

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.