LINC00482

Summary

LINC00482 (long intergenic non-protein coding RNA 482, HGNC:26816) is a long non-coding RNA gene on chromosome 17q25.3.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:26816
Approved symbol	LINC00482
Name	long intergenic non-protein coding RNA 482
Location	17q25.3
Locus type	RNA, long non-coding
Status	Approved
Aliases	FLJ39421
Ensembl gene	ENSG00000185168
Ensembl biotype	lncRNA
Entrez	284185
RNAcentral	URS000075DA9F — lncRNA, 2970 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 20 — 20 lncRNA

ENST00000332012, ENST00000577000, ENST00000773320, ENST00000773321, ENST00000773322, ENST00000773323, ENST00000773324, ENST00000773325, ENST00000773326, ENST00000773327, ENST00000773328, ENST00000773329, ENST00000773330, ENST00000773331, ENST00000773332, ENST00000773333, ENST00000773334, ENST00000773335, ENST00000773336, ENST00000773337

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000332012 — 4 exons

Exon	Start	End
ENSE00001323196	81303771	81305362
ENSE00001529059	81305666	81305817
ENSE00003984577	81307630	81307844
ENSE00003984578	81309185	81309278

Expression profiles

Bgee: expression breadth ubiquitous, 168 present calls, max score 98.90.

FANTOM5 (CAGE): breadth broad, TPM avg 0.3763 / max 13.1153, expressed in 219 samples.

FANTOM5 promoters (1 alternative TSS)

Promoter ID	TPM avg	Samples expressed
168686	0.3763	219

Top tissues by expression

213 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
colonic epithelium	UBERON:0000397	98.90	gold quality
bone marrow cell	CL:0002092	96.04	gold quality
lower esophagus mucosa	UBERON:0035834	85.10	gold quality
tendon of biceps brachii	UBERON:0008188	83.33	silver quality
kidney epithelium	UBERON:0004819	81.45	gold quality
nasal cavity epithelium	UBERON:0005384	80.44	gold quality
buccal mucosa cell	CL:0002336	80.21	silver quality
right lobe of liver	UBERON:0001114	79.92	gold quality
pancreatic ductal cell	CL:0002079	79.11	silver quality
superficial temporal artery	UBERON:0001614	78.37	gold quality
epithelial cell of pancreas	CL:0000083	77.54	gold quality
spleen	UBERON:0002106	76.95	gold quality
right lobe of thyroid gland	UBERON:0001119	76.75	gold quality
skeletal muscle tissue of rectus abdominis	UBERON:0004511	76.31	gold quality
secondary oocyte	CL:0000655	76.24	silver quality
skeletal muscle tissue of biceps brachii	UBERON:0004502	76.20	silver quality
mammary duct	UBERON:0001765	76.13	gold quality
epithelium of mammary gland	UBERON:0003244	76.10	gold quality
apex of heart	UBERON:0002098	75.11	gold quality
skeletal muscle tissue	UBERON:0001134	74.71	gold quality
transverse colon	UBERON:0001157	74.01	gold quality
liver	UBERON:0002107	73.92	gold quality
monocyte	CL:0000576	73.76	gold quality
gastrocnemius	UBERON:0001388	73.72	gold quality
upper arm skin	UBERON:0004263	73.23	gold quality
left lobe of thyroid gland	UBERON:0001120	73.16	gold quality
leukocyte	CL:0000738	73.01	gold quality
thyroid gland	UBERON:0002046	72.95	gold quality
muscle of leg	UBERON:0001383	72.73	gold quality
bone marrow	UBERON:0002371	72.24	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 0.

Experiment	Marker?	Max mean expression
E-ANND-3	no	1.25

Regulation

Is transcription factor: no

Literature-anchored findings (GeneRIF, showing 3)

• Silencing LINC00482 inhibits tumor-associated inflammation and angiogenesis through down-regulation of MMP-15 via FOXA1 in bladder cancer. (PMID:33323547)
• Extracellular vesicle-derived LINC00482 induces microglial M2 polarization to facilitate brain metastasis of NSCLC. (PMID:36963460)
• Identification and Characterization of a ceRNA Regulatory Network Involving LINC00482 and PRRC2B in Peripheral Blood Mononuclear Cells: Implications for COPD Pathogenesis and Diagnosis. (PMID:38348310)

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.