LINC00485

Summary

LINC00485 (long intergenic non-protein coding RNA 485, HGNC:27476) is a long non-coding RNA gene on chromosome 12q23.2.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:27476
Approved symbol	LINC00485
Name	long intergenic non-protein coding RNA 485
Location	12q23.2
Locus type	RNA, long non-coding
Status	Approved
Ensembl gene	ENSG00000258169
Ensembl biotype	lncRNA
Entrez	283432
RNAcentral	URS000075E149 — lncRNA, 3719 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 2 — 2 lncRNA

ENST00000547179, ENST00000734075

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000547179 — 5 exons

Exon	Start	End
ENSE00002325370	102824296	102824399
ENSE00002357867	102809280	102812616
ENSE00002359538	102821098	102821217
ENSE00002412278	102813868	102813972
ENSE00002412843	102822708	102822763

Expression profiles

Bgee: expression breadth broad, 36 present calls, max score 59.16.

FANTOM5 (CAGE): breadth tissue_specific, TPM avg 0.0192 / max 18.0007, expressed in 6 samples.

FANTOM5 promoters (1 alternative TSS)

Promoter ID	TPM avg	Samples expressed
132950	0.0192	6

Top tissues by expression

167 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
upper lobe of lung	UBERON:0008948	59.16	silver quality
right adrenal gland cortex	UBERON:0035827	49.02	gold quality
monocyte	CL:0000576	48.41	silver quality
right adrenal gland	UBERON:0001233	48.20	gold quality
right ovary	UBERON:0002118	46.92	gold quality
left adrenal gland	UBERON:0001234	46.84	gold quality
esophagogastric junction muscularis propria	UBERON:0035841	46.75	gold quality
adrenal cortex	UBERON:0001235	46.55	gold quality
left adrenal gland cortex	UBERON:0035825	46.51	gold quality
adrenal gland	UBERON:0002369	46.50	gold quality
smooth muscle tissue	UBERON:0001135	45.21	silver quality
minor salivary gland	UBERON:0001830	44.65	gold quality
skeletal muscle tissue of rectus abdominis	UBERON:0004511	43.37	gold quality
tibial artery	UBERON:0007610	43.16	silver quality
ascending aorta	UBERON:0001496	43.15	gold quality
aorta	UBERON:0000947	42.83	silver quality
tibial nerve	UBERON:0001323	42.67	gold quality
secondary oocyte	CL:0000655	42.57	gold quality
small intestine Peyer’s patch	UBERON:0003454	42.32	silver quality
omental fat pad	UBERON:0010414	42.31	silver quality
peritoneum	UBERON:0002358	42.27	silver quality
blood	UBERON:0000178	42.07	gold quality
heart left ventricle	UBERON:0002084	41.97	gold quality
skin of abdomen	UBERON:0001416	41.95	silver quality
adipose tissue of abdominal region	UBERON:0007808	41.91	silver quality
oviduct epithelium	UBERON:0004804	41.73	gold quality
vastus lateralis	UBERON:0001379	41.41	gold quality
quadriceps femoris	UBERON:0001377	41.37	gold quality
adult mammalian kidney	UBERON:0000082	41.34	gold quality
superficial temporal artery	UBERON:0001614	41.33	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 1.

Experiment	Marker?	Max mean expression
E-ANND-3	yes	3.27

Regulation

Is transcription factor: no

Literature-anchored findings (GeneRIF, showing 1)

• Long intergenic non-coding RNA LINC00485 exerts tumor-suppressive activity by regulating miR-581/EDEM1 axis in colorectal cancer. (PMID:33461166)

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.