LINC00487

Summary

LINC00487 (long intergenic non-protein coding RNA 487, HGNC:42947) is a long non-coding RNA gene on chromosome 2p25.2.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:42947
Approved symbol	LINC00487
Name	long intergenic non-protein coding RNA 487
Location	2p25.2
Locus type	RNA, long non-coding
Status	Approved
Aliases	FLJ42418
Ensembl gene	ENSG00000205837
Ensembl biotype	lncRNA
Entrez	400941
RNAcentral	URS000075B072 — lncRNA, 2145 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 11 — 11 lncRNA

ENST00000382045, ENST00000412528, ENST00000424179, ENST00000731579, ENST00000731580, ENST00000731581, ENST00000731582, ENST00000731583, ENST00000731584, ENST00000731585, ENST00000731586

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000382045 — 6 exons

Exon	Start	End
ENSE00001490747	6729168	6729662
ENSE00001490748	6730649	6730743
ENSE00001490749	6731155	6732260
ENSE00001490750	6732696	6732804
ENSE00001490753	6736623	6736715
ENSE00001683031	6770079	6770311

Expression profiles

Bgee: expression breadth ubiquitous, 149 present calls, max score 82.52.

Top tissues by expression

229 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
male germ line stem cell (sensu Vertebrata) in testis	CL:0000089 ∩ UBERON:0000473	82.52	gold quality
apex of heart	UBERON:0002098	66.75	gold quality
ganglionic eminence	UBERON:0004023	66.73	gold quality
buccal mucosa cell	CL:0002336	66.24	gold quality
hindlimb stylopod muscle	UBERON:0004252	63.97	gold quality
lymph node	UBERON:0000029	63.70	gold quality
right lung	UBERON:0002167	63.09	gold quality
tonsil	UBERON:0002372	63.02	gold quality
ventricular zone	UBERON:0003053	60.42	gold quality
vermiform appendix	UBERON:0001154	60.04	gold quality
olfactory segment of nasal mucosa	UBERON:0005386	58.89	gold quality
upper lobe of left lung	UBERON:0008952	58.75	gold quality
upper lobe of lung	UBERON:0008948	58.45	gold quality
putamen	UBERON:0001874	57.59	gold quality
descending thoracic aorta	UBERON:0002345	57.25	gold quality
heart left ventricle	UBERON:0002084	56.88	gold quality
nucleus accumbens	UBERON:0001882	56.85	gold quality
cardiac ventricle	UBERON:0002082	56.29	gold quality
caecum	UBERON:0001153	55.04	gold quality
right coronary artery	UBERON:0001625	54.91	gold quality
right lobe of liver	UBERON:0001114	54.79	gold quality
lower lobe of lung	UBERON:0008949	54.28	silver quality
muscle of leg	UBERON:0001383	54.17	gold quality
lung	UBERON:0002048	54.17	gold quality
granulocyte	CL:0000094	54.12	gold quality
heart	UBERON:0000948	54.01	gold quality
caudate nucleus	UBERON:0001873	54.00	gold quality
gastrocnemius	UBERON:0001388	53.40	gold quality
prefrontal cortex	UBERON:0000451	53.11	gold quality
right atrium auricular region	UBERON:0006631	52.84	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 0.

Experiment	Marker?	Max mean expression
E-ANND-3	no	3.09

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.