LINC00489

Summary

LINC00489 (long intergenic non-protein coding RNA 489, HGNC:43426) is a long non-coding RNA gene on chromosome 20q11.23.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:43426
Approved symbol	LINC00489
Name	long intergenic non-protein coding RNA 489
Location	20q11.23
Locus type	RNA, long non-coding
Status	Approved
Ensembl gene	ENSG00000225759
Ensembl biotype	lncRNA
Entrez	100861522
RNAcentral	URS000075AB21 — lncRNA, 548 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 1 — 1 lncRNA

ENST00000457816

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000457816 — 3 exons

Exon	Start	End
ENSE00001726986	37622829	37623119
ENSE00001728592	37622091	37622200
ENSE00001792165	37619298	37619439

Expression profiles

Bgee: expression breadth broad, 14 present calls, max score 64.20.

Top tissues by expression

14 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
sural nerve	UBERON:0015488	64.20	silver quality
heart	UBERON:0000948	59.94	gold quality
gastrocnemius	UBERON:0001388	52.59	gold quality
blood	UBERON:0000178	51.70	gold quality
prefrontal cortex	UBERON:0000451	50.83	gold quality
tibial artery	UBERON:0007610	49.84	gold quality
esophagus mucosa	UBERON:0002469	43.85	gold quality
muscle layer of sigmoid colon	UBERON:0035805	40.50	silver quality
skin of leg	UBERON:0001511	39.79	silver quality
right testis	UBERON:0004534	39.41	gold quality
body of pancreas	UBERON:0001150	36.84	silver quality
transverse colon	UBERON:0001157	36.64	silver quality
right frontal lobe	UBERON:0002810	32.14	silver quality
left testis	UBERON:0004533	29.84	silver quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 0.

Experiment	Marker?	Max mean expression
E-ANND-3	no	1.31

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.