LINC00494

Summary

LINC00494 (long intergenic non-protein coding RNA 494, HGNC:27657) is a long non-coding RNA gene on chromosome 20q13.13.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:27657
Approved symbol	LINC00494
Name	long intergenic non-protein coding RNA 494
Location	20q13.13
Locus type	RNA, long non-coding
Status	Approved
Ensembl gene	ENSG00000235621
Ensembl biotype	lncRNA
Entrez	284749
RNAcentral	URS000075AAA5 — lncRNA, 3610 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 17 — 17 lncRNA

ENST00000416742, ENST00000425021, ENST00000433094, ENST00000545181, ENST00000652930, ENST00000655482, ENST00000660785, ENST00000663665, ENST00000666125, ENST00000667132, ENST00000669055, ENST00000669689, ENST00000670744, ENST00000670842, ENST00000671184, ENST00000692154, ENST00000775434

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000416742 — 5 exons

Exon	Start	End
ENSE00001662238	48366474	48366633
ENSE00001705505	48366736	48367059
ENSE00001752248	48368080	48370629
ENSE00001754231	48364889	48365197
ENSE00001761949	48359950	48360150

Expression profiles

Bgee: expression breadth ubiquitous, 123 present calls, max score 87.65.

FANTOM5 (CAGE): breadth tissue_specific, TPM avg 0.2547 / max 24.2316, expressed in 105 samples.

FANTOM5 promoters (1 alternative TSS)

Promoter ID	TPM avg	Samples expressed
185118	0.2547	105

Top tissues by expression

214 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
male germ line stem cell (sensu Vertebrata) in testis	CL:0000089 ∩ UBERON:0000473	87.65	gold quality
sperm	CL:0000019	83.02	gold quality
right testis	UBERON:0004534	77.16	gold quality
left testis	UBERON:0004533	76.68	gold quality
spleen	UBERON:0002106	76.49	gold quality
bone marrow cell	CL:0002092	74.15	gold quality
testis	UBERON:0000473	73.91	gold quality
vermiform appendix	UBERON:0001154	72.06	gold quality
lymph node	UBERON:0000029	70.85	gold quality
colonic epithelium	UBERON:0000397	70.33	gold quality
granulocyte	CL:0000094	69.80	gold quality
adenohypophysis	UBERON:0002196	67.32	gold quality
pituitary gland	UBERON:0000007	66.80	gold quality
small intestine Peyer’s patch	UBERON:0003454	66.39	gold quality
caecum	UBERON:0001153	66.08	gold quality
endothelial cell	CL:0000115	65.74	gold quality
small intestine	UBERON:0002108	64.22	gold quality
hindlimb stylopod muscle	UBERON:0004252	61.99	gold quality
olfactory segment of nasal mucosa	UBERON:0005386	61.85	gold quality
pigmented layer of retina	UBERON:0001782	61.64	gold quality
tonsil	UBERON:0002372	61.59	gold quality
rectum	UBERON:0001052	61.50	gold quality
blood	UBERON:0000178	60.63	gold quality
duodenum	UBERON:0002114	59.01	gold quality
buccal mucosa cell	CL:0002336	56.98	gold quality
adult mammalian kidney	UBERON:0000082	56.84	gold quality
leukocyte	CL:0000738	56.64	gold quality
cortex of kidney	UBERON:0001225	56.56	gold quality
gall bladder	UBERON:0002110	55.73	gold quality
monocyte	CL:0000576	55.42	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 0.

Experiment	Marker?	Max mean expression
E-ANND-3	no	2.55

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.