LINC00507

Summary

LINC00507 (long intergenic non-protein coding RNA 507, HGNC:43558) is a long non-coding RNA gene on chromosome 12q24.32.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:43558
Approved symbol	LINC00507
Name	long intergenic non-protein coding RNA 507
Location	12q24.32
Locus type	RNA, long non-coding
Status	Approved
Ensembl gene	ENSG00000256193
Ensembl biotype	lncRNA
Entrez	100862680
RNAcentral	URS000075A808 — lncRNA, 2129 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 27 — 27 lncRNA

ENST00000540882, ENST00000542089, ENST00000544645, ENST00000653237, ENST00000653435, ENST00000654827, ENST00000656701, ENST00000656740, ENST00000657270, ENST00000657743, ENST00000657939, ENST00000658578, ENST00000659821, ENST00000662200, ENST00000662793, ENST00000664297, ENST00000666805, ENST00000667075, ENST00000668140, ENST00000668801, ENST00000670020, ENST00000670117, ENST00000670359, ENST00000670551, ENST00000670753, ENST00000671300, ENST00000741522

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000540882 — 5 exons

Exon	Start	End
ENSE00002207978	127949974	127951461
ENSE00002276526	127934290	127934349
ENSE00002285398	127944718	127944799
ENSE00003859112	127948824	127948922
ENSE00003881373	127915432	127915682

Expression profiles

Bgee: expression breadth ubiquitous, 116 present calls, max score 86.78.

FANTOM5 (CAGE): breadth tissue_specific, TPM avg 0.6884 / max 387.5476, expressed in 37 samples.

FANTOM5 promoters (2 alternative TSS)

Promoter ID	TPM avg	Samples expressed
128697	0.4326	32
128698	0.2558	35

Top tissues by expression

203 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
right frontal lobe	UBERON:0002810	86.78	gold quality
Brodmann (1909) area 9	UBERON:0013540	85.22	gold quality
dorsolateral prefrontal cortex	UBERON:0009834	85.15	gold quality
endothelial cell	CL:0000115	84.67	gold quality
prefrontal cortex	UBERON:0000451	82.95	gold quality
primary visual cortex	UBERON:0002436	82.81	gold quality
frontal cortex	UBERON:0001870	81.58	gold quality
male germ line stem cell (sensu Vertebrata) in testis	CL:0000089 ∩ UBERON:0000473	80.96	gold quality
neocortex	UBERON:0001950	80.58	gold quality
occipital lobe	UBERON:0002021	78.37	gold quality
anterior cingulate cortex	UBERON:0009835	77.67	gold quality
middle temporal gyrus	UBERON:0002771	77.21	gold quality
sural nerve	UBERON:0015488	75.76	gold quality
cerebral cortex	UBERON:0000956	75.48	gold quality
Brodmann (1909) area 23	UBERON:0013554	75.02	gold quality
superior frontal gyrus	UBERON:0002661	72.17	gold quality
right hemisphere of cerebellum	UBERON:0014890	70.19	gold quality
Brodmann (1909) area 46	UBERON:0006483	70.08	gold quality
colonic epithelium	UBERON:0000397	68.59	silver quality
bone marrow cell	CL:0002092	67.58	silver quality
forebrain	UBERON:0001890	65.68	gold quality
brain	UBERON:0000955	64.45	gold quality
postcentral gyrus	UBERON:0002581	62.98	gold quality
parietal lobe	UBERON:0001872	62.19	gold quality
cerebellar hemisphere	UBERON:0002245	61.16	gold quality
primordial germ cell in gonad	CL:0000670 ∩ UBERON:0000991	60.76	gold quality
mucosa of transverse colon	UBERON:0004991	59.57	gold quality
transverse colon	UBERON:0001157	59.47	gold quality
stromal cell of endometrium	CL:0002255	59.38	gold quality
corpus callosum	UBERON:0002336	59.02	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 1.

Experiment	Marker?	Max mean expression
E-ANND-3	yes	3.44

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.