LINC00508

Summary

LINC00508 (long intergenic non-protein coding RNA 508, HGNC:43559) is a long non-coding RNA gene on chromosome 12q24.32.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:43559
Approved symbol	LINC00508
Name	long intergenic non-protein coding RNA 508
Location	12q24.32
Locus type	RNA, long non-coding
Status	Approved
Ensembl gene	ENSG00000256971
Ensembl biotype	lncRNA
Entrez	104472718
RNAcentral	URS00007E4199 — lncRNA, 1428 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 7 — 7 lncRNA

ENST00000538901, ENST00000653038, ENST00000741352, ENST00000741353, ENST00000741354, ENST00000741355, ENST00000741356

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000538901 — 2 exons

Exon	Start	End
ENSE00002255405	127940595	127940735
ENSE00002272437	127950108	127950160

Expression profiles

Bgee: expression breadth broad, 46 present calls, max score 87.03.

FANTOM5 (CAGE): breadth tissue_specific, TPM avg 0.0156 / max 5.5876, expressed in 9 samples.

FANTOM5 promoters (1 alternative TSS)

Promoter ID	TPM avg	Samples expressed
134106	0.0156	9

Top tissues by expression

46 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
primordial germ cell in gonad	CL:0000670 ∩ UBERON:0000991	87.03	gold quality
male germ line stem cell (sensu Vertebrata) in testis	CL:0000089 ∩ UBERON:0000473	83.12	gold quality
corpus callosum	UBERON:0002336	69.63	gold quality
body of stomach	UBERON:0001161	68.76	gold quality
left adrenal gland cortex	UBERON:0035825	64.31	gold quality
right adrenal gland cortex	UBERON:0035827	63.93	gold quality
Ammon’s horn	UBERON:0001954	63.24	gold quality
right hemisphere of cerebellum	UBERON:0014890	60.83	gold quality
adrenal gland	UBERON:0002369	59.81	gold quality
Brodmann (1909) area 9	UBERON:0013540	59.42	gold quality
omental fat pad	UBERON:0010414	58.85	gold quality
dorsolateral prefrontal cortex	UBERON:0009834	58.05	gold quality
subcutaneous adipose tissue	UBERON:0002190	57.02	gold quality
monocyte	CL:0000576	56.99	gold quality
tibial nerve	UBERON:0001323	56.84	gold quality
superior frontal gyrus	UBERON:0002661	56.62	gold quality
thyroid gland	UBERON:0002046	56.38	gold quality
brain	UBERON:0000955	56.33	gold quality
endometrium	UBERON:0001295	56.13	gold quality
placenta	UBERON:0001987	55.87	gold quality
putamen	UBERON:0001874	55.62	gold quality
right frontal lobe	UBERON:0002810	54.79	gold quality
anterior cingulate cortex	UBERON:0009835	54.52	gold quality
frontal cortex	UBERON:0001870	54.47	gold quality
prefrontal cortex	UBERON:0000451	54.21	gold quality
islet of Langerhans	UBERON:0000006	53.58	gold quality
primary visual cortex	UBERON:0002436	53.12	gold quality
amygdala	UBERON:0001876	51.50	gold quality
skin of leg	UBERON:0001511	51.45	gold quality
hypothalamus	UBERON:0001898	51.08	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 0.

Experiment	Marker?	Max mean expression
E-ANND-3	no	0.32

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.