LINC00513

Summary

LINC00513 (long intergenic non-protein coding RNA 513, HGNC:43566) is a long non-coding RNA gene on chromosome 7q32.3.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:43566
Approved symbol	LINC00513
Name	long intergenic non-protein coding RNA 513
Location	7q32.3
Locus type	RNA, long non-coding
Status	Approved
Aliases	AC016831.7
Ensembl gene	ENSG00000233559
Ensembl biotype	lncRNA
Entrez	100506860
RNAcentral	URS000075E2F6 — lncRNA, 963 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 44 — 44 lncRNA

ENST00000447430, ENST00000608412, ENST00000653887, ENST00000664231, ENST00000666086, ENST00000846160, ENST00000846161, ENST00000846162, ENST00000846163, ENST00000846164, ENST00000846165, ENST00000846166, ENST00000846167, ENST00000846168, ENST00000846169, ENST00000846170, ENST00000846171, ENST00000846172, ENST00000846173, ENST00000846174, ENST00000846175, ENST00000846176, ENST00000846177, ENST00000846178, ENST00000846179, ENST00000846180, ENST00000846181, ENST00000846182, ENST00000846183, ENST00000846184, ENST00000846185, ENST00000846186, ENST00000846187, ENST00000846188, ENST00000846189, ENST00000846190, ENST00000846191, ENST00000846192, ENST00000846193, ENST00000846194, ENST00000846195, ENST00000846196, ENST00000846197, ENST00000846198

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000447430 — 5 exons

Exon	Start	End
ENSE00001714552	130862124	130862202
ENSE00001724885	130853720	130853796
ENSE00001729856	130914964	130915102
ENSE00001777294	130927562	130928649
ENSE00001780645	130915900	130916132

Expression profiles

Bgee: expression breadth ubiquitous, 158 present calls, max score 90.55.

FANTOM5 (CAGE): breadth broad, TPM avg 2.2617 / max 109.8054, expressed in 750 samples.

FANTOM5 promoters (8 alternative TSS)

Promoter ID	TPM avg	Samples expressed
81161	1.4484	522
81160	0.2621	131
81163	0.1580	55
81159	0.1157	50
81165	0.0951	37
81164	0.0948	35
81162	0.0519	18
81158	0.0358	13

Top tissues by expression

244 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
sural nerve	UBERON:0015488	90.55	gold quality
bone marrow cell	CL:0002092	85.40	gold quality
colonic epithelium	UBERON:0000397	84.42	gold quality
calcaneal tendon	UBERON:0003701	83.81	gold quality
male germ line stem cell (sensu Vertebrata) in testis	CL:0000089 ∩ UBERON:0000473	81.68	gold quality
primordial germ cell in gonad	CL:0000670 ∩ UBERON:0000991	81.44	gold quality
pancreatic ductal cell	CL:0002079	75.65	silver quality
tendon	UBERON:0000043	75.07	gold quality
rectum	UBERON:0001052	73.62	gold quality
hindlimb stylopod muscle	UBERON:0004252	73.08	gold quality
buccal mucosa cell	CL:0002336	71.20	gold quality
mucosa of transverse colon	UBERON:0004991	68.76	gold quality
adrenal tissue	UBERON:0018303	68.28	gold quality
ileal mucosa	UBERON:0000331	66.82	silver quality
corpus callosum	UBERON:0002336	66.29	gold quality
tonsil	UBERON:0002372	63.49	gold quality
blood	UBERON:0000178	62.94	gold quality
cerebellar vermis	UBERON:0004720	60.87	silver quality
liver	UBERON:0002107	60.66	gold quality
right lobe of thyroid gland	UBERON:0001119	60.35	gold quality
tendon of biceps brachii	UBERON:0008188	60.31	gold quality
transverse colon	UBERON:0001157	60.12	gold quality
left lobe of thyroid gland	UBERON:0001120	59.88	gold quality
stromal cell of endometrium	CL:0002255	59.69	gold quality
adult mammalian kidney	UBERON:0000082	59.36	gold quality
thyroid gland	UBERON:0002046	59.36	gold quality
right lobe of liver	UBERON:0001114	59.14	gold quality
adrenal gland	UBERON:0002369	58.27	gold quality
muscle of leg	UBERON:0001383	57.98	gold quality
left adrenal gland cortex	UBERON:0035825	57.64	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 1.

Experiment	Marker?	Max mean expression
E-ANND-3	yes	5.68

Regulation

Is transcription factor: no

Literature-anchored findings (GeneRIF, showing 1)

• Study data identify rs205764 and rs547311 functional promoter variants of linc00513 that contribute to increased level of linc00513 and confer susceptibility to systemic lupus erythematosus. (PMID:30619325)

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.