LINC00517

Summary

LINC00517 (long intergenic non-protein coding RNA 517, HGNC:19831) is a long non-coding RNA gene on chromosome 14q21.1.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:19831
Approved symbol	LINC00517
Name	long intergenic non-protein coding RNA 517
Location	14q21.1
Locus type	RNA, long non-coding
Status	Approved
Ensembl gene	ENSG00000259091
Ensembl biotype	lncRNA
Entrez	400208
RNAcentral	URS00001A2AB5 — lncRNA, 3460 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 2 — 2 lncRNA

ENST00000553396, ENST00000554257

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000553396 — 2 exons

Exon	Start	End
ENSE00002437727	37902016	37902372
ENSE00002529071	37900876	37901292

Expression profiles

Bgee: expression breadth broad, 76 present calls, max score 88.56.

FANTOM5 (CAGE): breadth tissue_specific, TPM avg 0.0892 / max 6.8913, expressed in 46 samples.

FANTOM5 promoters (1 alternative TSS)

Promoter ID	TPM avg	Samples expressed
142992	0.0892	46

Top tissues by expression

76 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
male germ line stem cell (sensu Vertebrata) in testis	CL:0000089 ∩ UBERON:0000473	88.56	gold quality
calcaneal tendon	UBERON:0003701	68.61	gold quality
stromal cell of endometrium	CL:0002255	64.26	gold quality
hindlimb stylopod muscle	UBERON:0004252	56.99	gold quality
skeletal muscle tissue	UBERON:0001134	56.11	silver quality
endometrium	UBERON:0001295	55.88	gold quality
placenta	UBERON:0001987	53.16	gold quality
blood	UBERON:0000178	52.03	gold quality
apex of heart	UBERON:0002098	51.93	gold quality
muscle of leg	UBERON:0001383	51.66	gold quality
pancreas	UBERON:0001264	49.82	silver quality
prefrontal cortex	UBERON:0000451	49.62	gold quality
lymph node	UBERON:0000029	49.15	silver quality
gall bladder	UBERON:0002110	48.26	gold quality
monocyte	CL:0000576	48.13	silver quality
liver	UBERON:0002107	47.94	silver quality
gastrocnemius	UBERON:0001388	47.61	gold quality
islet of Langerhans	UBERON:0000006	46.74	silver quality
left coronary artery	UBERON:0001626	46.44	gold quality
heart	UBERON:0000948	46.26	gold quality
tibial artery	UBERON:0007610	46.13	gold quality
popliteal artery	UBERON:0002250	46.06	gold quality
heart left ventricle	UBERON:0002084	45.86	gold quality
esophagogastric junction muscularis propria	UBERON:0035841	45.69	gold quality
urinary bladder	UBERON:0001255	45.60	silver quality
stomach	UBERON:0000945	44.84	gold quality
lung	UBERON:0002048	44.69	silver quality
prostate gland	UBERON:0002367	44.67	silver quality
lower esophagus	UBERON:0013473	44.62	gold quality
lower esophagus muscularis layer	UBERON:0035833	44.52	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 0.

Experiment	Marker?	Max mean expression
E-ANND-3	no	3.08

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.