LINC00524

Summary

LINC00524 (long intergenic non-protein coding RNA 524, HGNC:20118) is a long non-coding RNA gene on chromosome 14q32.31.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:20118
Approved symbol	LINC00524
Name	long intergenic non-protein coding RNA 524
Location	14q32.31
Locus type	RNA, long non-coding
Status	Approved
Ensembl gene	ENSG00000259023
Ensembl biotype	lncRNA
Entrez	338002
RNAcentral	URS00005FB03C — lncRNA, 418 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 19 — 19 lncRNA

ENST00000556987, ENST00000665068, ENST00000670271, ENST00000726431, ENST00000726432, ENST00000726433, ENST00000726434, ENST00000726435, ENST00000726436, ENST00000726437, ENST00000726438, ENST00000726439, ENST00000726440, ENST00000726441, ENST00000726442, ENST00000726443, ENST00000726444, ENST00000726445, ENST00000726446

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000556987 — 2 exons

Exon	Start	End
ENSE00003867077	101407743	101408258
ENSE00004050986	101405987	101406224

Expression profiles

Bgee: expression breadth broad, 96 present calls, max score 87.37.

Top tissues by expression

101 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
bone marrow	UBERON:0002371	87.37	silver quality
skeletal muscle tissue	UBERON:0001134	87.25	silver quality
thymus	UBERON:0002370	83.79	silver quality
quadriceps femoris	UBERON:0001377	64.14	gold quality
lymph node	UBERON:0000029	63.55	gold quality
cerebellar vermis	UBERON:0004720	63.05	gold quality
placenta	UBERON:0001987	58.51	gold quality
prefrontal cortex	UBERON:0000451	58.16	gold quality
islet of Langerhans	UBERON:0000006	56.87	gold quality
liver	UBERON:0002107	55.79	gold quality
left testis	UBERON:0004533	55.58	gold quality
monocyte	CL:0000576	55.00	gold quality
tonsil	UBERON:0002372	54.79	gold quality
sural nerve	UBERON:0015488	54.63	silver quality
testis	UBERON:0000473	54.61	gold quality
gall bladder	UBERON:0002110	54.52	gold quality
cerebellum	UBERON:0002037	53.51	gold quality
right lobe of liver	UBERON:0001114	52.96	gold quality
nucleus accumbens	UBERON:0001882	52.94	gold quality
olfactory segment of nasal mucosa	UBERON:0005386	52.24	gold quality
hindlimb stylopod muscle	UBERON:0004252	52.09	gold quality
vermiform appendix	UBERON:0001154	52.06	gold quality
right testis	UBERON:0004534	51.46	gold quality
muscle of leg	UBERON:0001383	51.45	gold quality
left uterine tube	UBERON:0001303	51.44	gold quality
blood	UBERON:0000178	51.29	gold quality
right hemisphere of cerebellum	UBERON:0014890	51.02	gold quality
gastrocnemius	UBERON:0001388	50.91	gold quality
endocervix	UBERON:0000458	50.47	gold quality
fundus of stomach	UBERON:0001160	49.77	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 0.

Experiment	Marker?	Max mean expression
E-ANND-3	no	0.49

Regulation

Is transcription factor: no

Literature-anchored findings (GeneRIF, showing 1)

• A novel long non-coding RNA LINC00524 facilitates invasion and metastasis through interaction with TDP43 in breast cancer. (PMID:38568058)

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.