LINC00558
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Summary
LINC00558 (long intergenic non-protein coding RNA 558, HGNC:43702) is a long non-coding RNA gene on chromosome 13q14.3.
At a glance
- Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).
Identifiers
Gene identifiers
| Field | Value |
|---|---|
| HGNC ID | HGNC:43702 |
| Approved symbol | LINC00558 |
| Name | long intergenic non-protein coding RNA 558 |
| Location | 13q14.3 |
| Locus type | RNA, long non-coding |
| Status | Approved |
| Ensembl gene | ENSG00000261517 |
| Ensembl biotype | lncRNA |
| Entrez | 100861552 |
| RNAcentral | URS000075E4AB — lncRNA, 3175 nt, 1 organism(s) |
Gene structure
Transcript identifiers
Ensembl transcripts: 4 — 4 lncRNA
ENST00000569422, ENST00000655355, ENST00000663173, ENST00000666941
RefSeq mRNA: 0 — MANE Select: None
Canonical transcript exons
ENST00000569422 — 6 exons
| Exon | Start | End |
|---|---|---|
| ENSE00002588909 | 53873452 | 53876119 |
| ENSE00002595617 | 53870465 | 53870527 |
| ENSE00002604958 | 53815419 | 53815493 |
| ENSE00002610665 | 53838739 | 53838789 |
| ENSE00002616154 | 53844345 | 53844522 |
| ENSE00002620773 | 53840683 | 53840810 |
Expression profiles
Bgee: expression breadth broad, 23 present calls, max score 54.85.
Top tissues by expression
167 total, by Bgee expression score (0-100, higher = more expressed):
| Tissue | Anatomy ID | Expression score | Quality |
|---|---|---|---|
| monocyte | CL:0000576 | 54.85 | gold quality |
| esophagogastric junction muscularis propria | UBERON:0035841 | 53.19 | gold quality |
| lower esophagus muscularis layer | UBERON:0035833 | 50.70 | gold quality |
| Brodmann (1909) area 9 | UBERON:0013540 | 50.40 | gold quality |
| right testis | UBERON:0004534 | 46.61 | gold quality |
| left testis | UBERON:0004533 | 45.99 | gold quality |
| hindlimb stylopod muscle | UBERON:0004252 | 45.45 | silver quality |
| testis | UBERON:0000473 | 45.39 | gold quality |
| primordial germ cell in gonad | CL:0000670 ∩ UBERON:0000991 | 45.18 | silver quality |
| pancreas | UBERON:0001264 | 44.60 | gold quality |
| upper lobe of lung | UBERON:0008948 | 44.28 | silver quality |
| stomach | UBERON:0000945 | 43.92 | gold quality |
| small intestine | UBERON:0002108 | 43.84 | gold quality |
| skeletal muscle tissue of rectus abdominis | UBERON:0004511 | 43.37 | gold quality |
| secondary oocyte | CL:0000655 | 42.57 | gold quality |
| cortex of kidney | UBERON:0001225 | 42.39 | gold quality |
| blood | UBERON:0000178 | 42.13 | gold quality |
| heart left ventricle | UBERON:0002084 | 41.97 | gold quality |
| vastus lateralis | UBERON:0001379 | 41.41 | gold quality |
| quadriceps femoris | UBERON:0001377 | 41.37 | gold quality |
| superficial temporal artery | UBERON:0001614 | 41.33 | gold quality |
| body of stomach | UBERON:0001161 | 41.18 | silver quality |
| cardiac ventricle | UBERON:0002082 | 41.15 | gold quality |
| bone marrow | UBERON:0002371 | 41.14 | gold quality |
| skeletal muscle tissue | UBERON:0001134 | 41.10 | gold quality |
| palpebral conjunctiva | UBERON:0001812 | 41.10 | gold quality |
| dorsolateral prefrontal cortex | UBERON:0009834 | 41.00 | silver quality |
| anatomical system | UBERON:0000467 | 40.99 | gold quality |
| mucosa of paranasal sinus | UBERON:0005030 | 40.98 | gold quality |
| multicellular organism | UBERON:0000468 | 40.95 | gold quality |
Single-cell (SCXA)
Detected in 1 experiment(s), a significant marker in 1.
| Experiment | Marker? | Max mean expression |
|---|---|---|
| E-ANND-3 | yes | 3.44 |
Regulation
Is transcription factor: no
Cross-species orthologs
0 orthologs
Protein
Non-coding RNA — no protein product; not a drug target.
Function
No curated pathway, Gene-Ontology, or interaction data.
Disease & clinical
No curated disease, variant, or cancer-driver associations.
Drugs & pharmacology
No drug or pharmacology data — not an established drug target.
Related Atlas pages
- Disease cohort memberships (association, not causation — diseases whose associated-gene cohort lists this gene; a subset are also under Associated diseases): brain aneurysm